Use of on-line our measurements to monitor and improve insect cell cultures for recombinant protein production

M Lecina; A Casablancas; A Soley; C Vela; E Espuña; J De Gracia; JJ Cairó; F Gódia

Use of on-line our measurements to monitor and improve insect cell cultures for recombinant protein production

M Lecina
, A Casablancas
, A Soley
, C Vela
, E Espuña
, J De Gracia
, JJ Cairó
, F Gódia

Research output: Book chapter › Conference contribution › peer-review

Abstract

On-line oxygen uptake rate measurements using a dynamic model are applied to Sf9 cultures infected with recombinant baculovirus. This measurement allows a sensitive monitoring of cell growth and post-infection process. Also, results are given on fed-batch and perfusion cultures were 8-10 (.) 10(6) cells/ml can be achieved by automatically adjusting the medium fed-rate on the basis of OUR on-line measurements.

Original language	English
Title of host publication	Animal Cell Technology Meets Genomics
Editors	F Godia, M Fussenegger
Publisher	Springer Nature
Pages	779-781
Number of pages	3
ISBN (Print)	1-4020-2791-5
Publication status	Published - 2005
Externally published	Yes
Event	18th Meeting of the European-Society-of-Animal-Cell-Technology (ESACT) - Granada, Spain Duration: 11 May 2003 → 14 May 2003

Conference

Conference	18th Meeting of the European-Society-of-Animal-Cell-Technology (ESACT)
Country/Territory	Spain
City	Granada
Period	11/05/03 → 14/05/03

Cite this

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title = "Use of on-line our measurements to monitor and improve insect cell cultures for recombinant protein production",

abstract = "On-line oxygen uptake rate measurements using a dynamic model are applied to Sf9 cultures infected with recombinant baculovirus. This measurement allows a sensitive monitoring of cell growth and post-infection process. Also, results are given on fed-batch and perfusion cultures were 8-10 (.) 10(6) cells/ml can be achieved by automatically adjusting the medium fed-rate on the basis of OUR on-line measurements.",

author = "M Lecina and A Casablancas and A Soley and C Vela and E Espu{\~n}a and \{De Gracia\}, J and JJ Cair{\'o} and F G{\'o}dia",

year = "2005",

language = "English",

isbn = "1-4020-2791-5",

pages = "779--781",

editor = "F Godia and M Fussenegger",

booktitle = "Animal Cell Technology Meets Genomics",

publisher = "Springer Nature",

address = "United Kingdom",

note = "18th Meeting of the European-Society-of-Animal-Cell-Technology (ESACT) ; Conference date: 11-05-2003 Through 14-05-2003",

}

Lecina, M, Casablancas, A, Soley, A, Vela, C, Espuña, E, De Gracia, J, Cairó, JJ & Gódia, F 2005, Use of on-line our measurements to monitor and improve insect cell cultures for recombinant protein production. in F Godia & M Fussenegger (eds), Animal Cell Technology Meets Genomics. Springer Nature, pp. 779-781, 18th Meeting of the European-Society-of-Animal-Cell-Technology (ESACT), Granada, Spain, 11/05/03.

TY - GEN

T1 - Use of on-line our measurements to monitor and improve insect cell cultures for recombinant protein production

AU - Lecina, M

AU - Casablancas, A

AU - Soley, A

AU - Vela, C

AU - Espuña, E

AU - De Gracia, J

AU - Cairó, JJ

AU - Gódia, F

PY - 2005

Y1 - 2005

N2 - On-line oxygen uptake rate measurements using a dynamic model are applied to Sf9 cultures infected with recombinant baculovirus. This measurement allows a sensitive monitoring of cell growth and post-infection process. Also, results are given on fed-batch and perfusion cultures were 8-10 (.) 10(6) cells/ml can be achieved by automatically adjusting the medium fed-rate on the basis of OUR on-line measurements.

AB - On-line oxygen uptake rate measurements using a dynamic model are applied to Sf9 cultures infected with recombinant baculovirus. This measurement allows a sensitive monitoring of cell growth and post-infection process. Also, results are given on fed-batch and perfusion cultures were 8-10 (.) 10(6) cells/ml can be achieved by automatically adjusting the medium fed-rate on the basis of OUR on-line measurements.

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:000228864200162&DestLinkType=FullRecord&DestApp=WOS_CPL

M3 - Conference contribution

SN - 1-4020-2791-5

SP - 779

EP - 781

BT - Animal Cell Technology Meets Genomics

A2 - Godia, F

A2 - Fussenegger, M

PB - Springer Nature

T2 - 18th Meeting of the European-Society-of-Animal-Cell-Technology (ESACT)

Y2 - 11 May 2003 through 14 May 2003

ER -

Use of on-line our measurements to monitor and improve insect cell cultures for recombinant protein production

Abstract

Conference

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