THE PHOTOPHYSICAL PROPERTIES OF PORPHYCENES: POTENTIAL PHOTODYNAMIC THERAPY AGENTS

Pedro F. Aramendia, Robert W. Redmond, Santiago Nonell, Wolfang Schuster, Silvia E. Braslavsky, Kurt Schaffner, Emanuel Vogel

Producció científica: Article en revista indexadaArticleAvaluat per experts

112 Cites (Scopus)

Resum

Porphycene and a tetra‐n‐propyl derivative remained unaltered on irradiation in toluene at room temperature. Quantum yields of fluorescence, S T intersystem crossing, and singlet molecular oxygen sensitization, as well as lifetimes of the singlet and triplet excited states were measured. In view of their structural relationship to porphyrin, their high absorption above 620 nm, their stability towards photooxidation, and their high quantum yields of fluorescence and singlet oxygen sensitization, these compounds qualify as potential agents for tumor marking and photodynamic therapy.

Idioma originalAnglès
Pàgines (de-a)555-559
Nombre de pàgines5
RevistaPhotochemistry and Photobiology
Volum44
Número5
DOIs
Estat de la publicacióPublicada - de nov. 1986
Publicat externament

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