Boron-Wittig olefination with: Gem -bis(boryl)alkanes

Ana B. Cuenca, Elena Fernández

Producció científica: Article en revista indexadaArticle de revisió (sistemàtica)Avaluat per experts

52 Cites (Scopus)


The condensation of easy manageable lithium α-bis(boryl)carbanions with carbonyl derivatives, the so-called boron-Wittig reaction, allows for the straightforward and often stereoselective formation of synthetically highly versatile metalloid-substituted alkenes, which are key building blocks on route to all-carbon substituted olefins. In this Tutorial review the concept behind this olefination reaction and its application to ketones, aldehydes and other carbonyl derivatives, such amides, ester and carboxylic acids, are presented in a systematic manner. A special emphasis has been placed on parameters controlling the stereochemical outcome of these transformations. To illustrate the great synthetic potential of this new methodological tool, a section is also included covering a selection of applications of the boron-Wittig reaction to target compounds via subsequent C-C bond-forming process.

Idioma originalAnglès
Pàgines (de-a)72-86
Nombre de pàgines15
RevistaChemical Society Reviews
Estat de la publicacióPublicada - 7 de gen. 2021


Navegar pels temes de recerca de 'Boron-Wittig olefination with: Gem -bis(boryl)alkanes'. Junts formen un fingerprint únic.

Com citar-ho