Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

Pedro Victory; JoséI I. Borrell; Anton Vidal-Ferran; Elvira Montenegro; M. Luisa Jimeno

doi:10.3987/com-93-6412

Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

Pedro Victory^*
, JoséI I. Borrell
, Anton Vidal-Ferran
, Elvira Montenegro
, M. Luisa Jimeno

^*Autor/a de correspondencia de este trabajo

Producción científica: Artículo en revista indizada › Artículo › revisión exhaustiva

25 Citas (Scopus)

Resumen

The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.

Idioma original	Inglés
Páginas (desde-hasta)	2273-2280
Número de páginas	8
Publicación	Heterocycles
Volumen	36
N.º	10
DOI	https://doi.org/10.3987/com-93-6412
Estado	Publicada - 1 oct 1993

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abstract = "The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.",

author = "Pedro Victory and Borrell, \{Jos{\'e}I I.\} and Anton Vidal-Ferran and Elvira Montenegro and Jimeno, \{M. Luisa\}",

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AU - Victory, Pedro

AU - Borrell, JoséI I.

AU - Vidal-Ferran, Anton

AU - Montenegro, Elvira

AU - Jimeno, M. Luisa

PY - 1993/10/1

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AB - The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.

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Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

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