Revisiting the ‘One Material Fits All’ Rule for Cancer Nanotherapy

João Conde, Nuria Oliva, Natalie Artzi

Producción científica: Artículo en revista indizadaRecensiónrevisión exhaustiva

6 Citas (Scopus)


The promise of (nano)biomaterials for the treatment of cancer can only be realized following a comprehensive scrutiny of the tumor microenvironment. The generic use of ‘inert’ vehicles that deliver a specific cargo to treat a range of cancer types and disease states obeys the ‘one material fits all’ rule. However, this approach leads to suboptimal and unpredictable clinical outcomes. The key factors constructing the tumor milieu should guide the design of disease-responsive materials. Given the growing availability of nanomaterials for cancer therapy, a material that responds to each patient's needs and, hence, reacts in a graded manner based on disease cues, would pave the way to precision materials for cancer therapy.

Idioma originalInglés
Páginas (desde-hasta)618-626
Número de páginas9
PublicaciónTrends in Biotechnology
EstadoPublicada - 1 ago 2016
Publicado de forma externa


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