TY - JOUR
T1 - Relationship between marital status and incidence of type 2 diabetes mellitus in a Brazilian rural population
T2 - The Baependi Heart Study
AU - De Oliveira, Camila Mac Iel
AU - Tureck, Luciane Viater
AU - Alvares, Danilo
AU - Liu, Chunyu
AU - Horimoto, Andrea Roseli Vancan Russo
AU - Balcells, Mercedes
AU - De Oliveira Alvim, Rafael
AU - Krieger, Jose Eduardo
AU - Pereira, Alexandre Costa
N1 - Publisher Copyright:
© 2020 de Oliveira et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2020/8
Y1 - 2020/8
N2 - Many factors influence the incidence of type 2 diabetes mellitus (T2DM). Here, we investigated the associations between socio-demographic characteristics and familial history with the 5-year incidence of T2DM in a family-based study conducted in Brazil. T2DM was defined as baseline fasting blood glucose ≥ 126 mg/dL or the use of any hypoglycaemic drug. We excluded individuals with T2DM at baseline or if they did not attend two examination cycles. After exclusions, we evaluated a sample of 1,125 participants, part of the Baependi Heart Study (BHS). Mixed-effects logistic regression models were used to assess T2DM incident given different characteristics. At the 5-year follow-up, the incidence of T2DM was 6.7% (7.2% men and 6.3% women). After adjusting for age, sex, and education status, the model that combined marital and occupation status, skin color, and familial history of T2DM provided the best prediction for T2DM incidence. Only marital status was independently associated with T2DM incidence. Individuals that remained married, despite having significantly increased their weight, were significantly less likely to develop diabetes than their divorced counterparts.
AB - Many factors influence the incidence of type 2 diabetes mellitus (T2DM). Here, we investigated the associations between socio-demographic characteristics and familial history with the 5-year incidence of T2DM in a family-based study conducted in Brazil. T2DM was defined as baseline fasting blood glucose ≥ 126 mg/dL or the use of any hypoglycaemic drug. We excluded individuals with T2DM at baseline or if they did not attend two examination cycles. After exclusions, we evaluated a sample of 1,125 participants, part of the Baependi Heart Study (BHS). Mixed-effects logistic regression models were used to assess T2DM incident given different characteristics. At the 5-year follow-up, the incidence of T2DM was 6.7% (7.2% men and 6.3% women). After adjusting for age, sex, and education status, the model that combined marital and occupation status, skin color, and familial history of T2DM provided the best prediction for T2DM incidence. Only marital status was independently associated with T2DM incidence. Individuals that remained married, despite having significantly increased their weight, were significantly less likely to develop diabetes than their divorced counterparts.
UR - http://www.scopus.com/inward/record.url?scp=85089054038&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0236869
DO - 10.1371/journal.pone.0236869
M3 - Article
C2 - 32745127
AN - SCOPUS:85089054038
SN - 1932-6203
VL - 15
JO - PLoS ONE
JF - PLoS ONE
IS - 8 August
M1 - e0236869
ER -
