Resumen
A long-range optimized P.E.HSQC experiment, named P.E.HSQMBC, is proposed for the simultaneous measurement of a complete set of homonuclear and heteronuclear coupling constants from a single 2D cross-peak. The sign and the magnitude of proton-proton coupling constants are measured along the direct dimension from the relative E.COSY-type multiplet pattern displacement due to the passive one-bond coupling constant splitting generated in the indirect dimension. On the other hand, long-range proton-carbon coupling constants are independently determined in the detected dimension from a traditional fitting analysis of antiphase multiplet patterns or, more conveniently, from the IPAP multiplet displacement obtained from extended HSQMBC experiments.
Idioma original | Inglés |
---|---|
Páginas (desde-hasta) | 101-106 |
Número de páginas | 6 |
Publicación | Journal of Magnetic Resonance |
Volumen | 224 |
DOI | |
Estado | Publicada - nov 2012 |
Publicado de forma externa | Sí |