Mixed monolayers composed of PC/PS/Chol. Interaction with opioid molecules

F. Reig*, C. Mestres, I. Haro, G. Valencia, J. M.García Antón, M. A. Alsina

*Autor correspondiente de este trabajo

Producción científica: Artículo en revista indizadaArtículorevisión exhaustiva

8 Citas (Scopus)

Resumen

The miscibility of phosphatidylserine, phosphatidylcholine, and cholesterol in monolayers were studied. The influence of sodium and calcium ions in this system was determined. The compression isotherms of mixed monolayers of the above cited three components spread on subphases containing opiate molecules are elucidated. Moreover, the penetration kinetics of opiate molecules in these mixed monolayers was also recorded. The results show that the presence of cholesterol always lowers the penetration of opioid molecules; this effect is weaken for meperidine, the most hydrophobic of the molecules assayed.

Idioma originalInglés
Páginas (desde-hasta)139-144
Número de páginas6
PublicaciónColloid and Polymer Science
Volumen267
N.º2
DOI
EstadoPublicada - feb 1989
Publicado de forma externa

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