Interaction of opioid molecules with PS, PC and PS/PC monolayers

M. A. Alsina; C. Mestres; G. Valencia; J. M.García Antón; F. Reig

doi:10.1007/BF01417867

Interaction of opioid molecules with PS, PC and PS/PC monolayers

M. A. Alsina, C. Mestres, G. Valencia, J. M.García Antón, F. Reig

Producción científica: Artículo en revista indizada › Artículo › revisión exhaustiva

4 Citas (Scopus)

Resumen

The interaction between opiate molecules and phosphatidylserine (PS) or phosphatidylcholine (PC) has been studied on compression isotherms and penetration kinetics. Phosphatidylcholine-opiate interactions are weak and similar in magnitude for all opiate molecules. On contrary, PS and PS/PC interact strongly and differently with opiate molecules. The differences in penetration are not directly related to the pKa or hydrophobicity of the molecules.

Idioma original	Inglés
Páginas (desde-hasta)	832-835
Número de páginas	4
Publicación	Colloid and Polymer Science
Volumen	266
N.º	9
DOI	https://doi.org/10.1007/BF01417867
Estado	Publicada - sept 1988
Publicado de forma externa	Sí

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title = "Interaction of opioid molecules with PS, PC and PS/PC monolayers",

abstract = "The interaction between opiate molecules and phosphatidylserine (PS) or phosphatidylcholine (PC) has been studied on compression isotherms and penetration kinetics. Phosphatidylcholine-opiate interactions are weak and similar in magnitude for all opiate molecules. On contrary, PS and PS/PC interact strongly and differently with opiate molecules. The differences in penetration are not directly related to the pKa or hydrophobicity of the molecules.",

keywords = "Opiates, monolayers, penetration kinetics, phosphatidylcholine, phosphatidylserine",

author = "Alsina, {M. A.} and C. Mestres and G. Valencia and Ant{\'o}n, {J. M.Garc{\'i}a} and F. Reig",

year = "1988",

month = sep,

doi = "10.1007/BF01417867",

language = "English",

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T1 - Interaction of opioid molecules with PS, PC and PS/PC monolayers

AU - Alsina, M. A.

AU - Mestres, C.

AU - Valencia, G.

AU - Antón, J. M.García

AU - Reig, F.

PY - 1988/9

Y1 - 1988/9

N2 - The interaction between opiate molecules and phosphatidylserine (PS) or phosphatidylcholine (PC) has been studied on compression isotherms and penetration kinetics. Phosphatidylcholine-opiate interactions are weak and similar in magnitude for all opiate molecules. On contrary, PS and PS/PC interact strongly and differently with opiate molecules. The differences in penetration are not directly related to the pKa or hydrophobicity of the molecules.

AB - The interaction between opiate molecules and phosphatidylserine (PS) or phosphatidylcholine (PC) has been studied on compression isotherms and penetration kinetics. Phosphatidylcholine-opiate interactions are weak and similar in magnitude for all opiate molecules. On contrary, PS and PS/PC interact strongly and differently with opiate molecules. The differences in penetration are not directly related to the pKa or hydrophobicity of the molecules.

KW - Opiates

KW - monolayers

KW - penetration kinetics

KW - phosphatidylcholine

KW - phosphatidylserine

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U2 - 10.1007/BF01417867

DO - 10.1007/BF01417867

M3 - Article

AN - SCOPUS:0024068938

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VL - 266

SP - 832

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JO - Colloid and Polymer Science

JF - Colloid and Polymer Science

IS - 9

ER -

Interaction of opioid molecules with PS, PC and PS/PC monolayers

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