From over-stoichiometric to sub-stoichiometric enantioselective protonation with 2-sulfinyl alcohols: A view in perspective

Mercedes Medio-Simón; Pedro Alemán; Ana Cuenca; Jesús Gil; Nuria Rodríguez; Gregorio Asensio

doi:10.3998/ark.5550190.0006.924

From over-stoichiometric to sub-stoichiometric enantioselective protonation with 2-sulfinyl alcohols: A view in perspective

Mercedes Medio-Simón
, Pedro Alemán
, Ana Cuenca
, Jesús Gil
, Nuria Rodríguez
, Gregorio Asensio^*

^*Autor/a de correspondencia de este trabajo

Producción científica: Artículo en revista indizada › Recensión › revisión exhaustiva

1 Cita (Scopus)

Resumen

A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared.

Idioma original	Inglés
Páginas (desde-hasta)	266-286
Número de páginas	21
Publicación	Arkivoc
Volumen	2005
N.º	9
DOI	https://doi.org/10.3998/ark.5550190.0006.924
Estado	Publicada - 8 abr 2005
Publicado de forma externa	Sí

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10.3998/ark.5550190.0006.924

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title = "From over-stoichiometric to sub-stoichiometric enantioselective protonation with 2-sulfinyl alcohols: A view in perspective",

abstract = "A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared.",

keywords = "Enantioselective protonation, Enolates, Sulfinyl alcohols",

author = "Mercedes Medio-Sim{\'o}n and Pedro Alem{\'a}n and Ana Cuenca and Jes{\'u}s Gil and Nuria Rodr{\'i}guez and Gregorio Asensio",

year = "2005",

month = apr,

day = "8",

doi = "10.3998/ark.5550190.0006.924",

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TY - JOUR

T1 - From over-stoichiometric to sub-stoichiometric enantioselective protonation with 2-sulfinyl alcohols

T2 - A view in perspective

AU - Medio-Simón, Mercedes

AU - Alemán, Pedro

AU - Cuenca, Ana

AU - Gil, Jesús

AU - Rodríguez, Nuria

AU - Asensio, Gregorio

PY - 2005/4/8

Y1 - 2005/4/8

N2 - A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared.

AB - A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared.

KW - Enantioselective protonation

KW - Enolates

KW - Sulfinyl alcohols

UR - https://www.scopus.com/pages/publications/20044386201

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:000235707600024&DestLinkType=FullRecord&DestApp=WOS_CPL

U2 - 10.3998/ark.5550190.0006.924

DO - 10.3998/ark.5550190.0006.924

M3 - Review

AN - SCOPUS:20044386201

SN - 1424-6376

VL - 2005

SP - 266

EP - 286

JO - Arkivoc

JF - Arkivoc

IS - 9

ER -

From over-stoichiometric to sub-stoichiometric enantioselective protonation with 2-sulfinyl alcohols: A view in perspective

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