Resumen
A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared.
Idioma original | Inglés |
---|---|
Páginas (desde-hasta) | 266-286 |
Número de páginas | 21 |
Publicación | Arkivoc |
Volumen | 2005 |
N.º | 9 |
Estado | Publicada - 8 abr 2005 |
Publicado de forma externa | Sí |