Effectiveness and safety of Stevia rebaudiana dried leaves as an adjuvant in the short-term treatment of type 2 diabetes: A randomized, controlled, cross-over and double-blinded trial

Título traducido de la contribución: Effectiveness and safety of Stevia rebaudiana dried leaves as an adjuvant in the short-term treatment of type 2 diabetes: A randomized, controlled, cross-over and double-blinded trial

Maria Rosa Rifà Ros, Àngels Pallarés Martí, Miriam Rodríguez Monforte, Genís Carrasco, Youssef Nava, Oriol Pallarés, Isabel Pérez-Pérez

Producción científica: Artículo en revista indizadaArtículo

Resumen

"Recent randomized controlled trials have demonstrated the utility of stevioside and related compounds, extracted and refined from stevia leaf plant, to improve blood glucose and blood pressure in patients with type 2 diabetes. However, up till date, no well-designed trials have shown that the dried leaves of the stevia plant have similar effects in medical use. A randomized, controlled, cross-over and double-blinded study was conducted to assess the effectiveness and safety of Stevia rebaudiana leaves to reduce blood glucose and mean arterial pressure in Sahrawi patients with type 2 diabetes. One hundred and fourteen patients (80 women and 34 men) participated in a cross-over study consisting of an intake of tea sweetened with dried leaves of S. rebaudiana (study group) or refined sugar (control group), after a wash out period of two days. Capillary blood glucose, hearth rate and blood pressure were then determined at minutes 0 (baseline), 30, 60, 120 and 240 after the ingestion. In all patients, blood glucose reduction of -35.8% (95%CI -27.0 to -44.6%) were observed in the S. rebaudiana group compared to an increase in the control group (+8.1%, 95%CI 3.1 to 13.2% [p
Título traducido de la contribuciónEffectiveness and safety of Stevia rebaudiana dried leaves as an adjuvant in the short-term treatment of type 2 diabetes: A randomized, controlled, cross-over and double-blinded trial
Idioma originalInglés
Páginas (desde-hasta)16-26
Número de páginas11
PublicaciónJornal of medicinal plant and herbal Therapy Research
Volumen3
N.º2
DOI
EstadoPublicada - 1 jun 2015

Huella

Profundice en los temas de investigación de 'Effectiveness and safety of Stevia rebaudiana dried leaves as an adjuvant in the short-term treatment of type 2 diabetes: A randomized, controlled, cross-over and double-blinded trial'. En conjunto forman una huella única.

Citar esto