Cationic phthalocyanine dendrimers as potential antimicrobial photosensitisers

Rubén Ruiz-González; Francesca Setaro; Òscar Gulías; Montserrat Agut; Uwe Hahn; Tomás Torres; Santi Nonell

doi:10.1039/c7ob02270k

Cationic phthalocyanine dendrimers as potential antimicrobial photosensitisers

Rubén Ruiz-González
, Francesca Setaro
, Òscar Gulías
, Montserrat Agut
, Uwe Hahn^*
, Tomás Torres
, Santi Nonell

^*Autor/a de correspondencia de este trabajo

Producción científica: Artículo en revista indizada › Artículo › revisión exhaustiva

30 Citas (Scopus)

Resumen

In the present study we describe the synthesis, photophysical properties and the photoinactivation performance against representative microorganisms of two families of cationic dendrimeric phthalocyanines as potential photosensitisers. Four charged dendrimeric compounds varying in their degree of ionicity (4 or 8 positive charges) and the coordinating metal (zinc or ruthenium) are compared and assessed as potential photosensitising agents in terms of their antimicrobial activity.

Idioma original	Inglés
Páginas (desde-hasta)	9008-9017
Número de páginas	10
Publicación	Organic and Biomolecular Chemistry
Volumen	15
N.º	42
Fecha en línea anticipada	18 oct 2017
DOI	https://doi.org/10.1039/c7ob02270k
Estado	Publicada - 14 nov 2017

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AU - Ruiz-González, Rubén

AU - Setaro, Francesca

AU - Gulías, Òscar

AU - Agut, Montserrat

AU - Hahn, Uwe

AU - Torres, Tomás

AU - Nonell, Santi

PY - 2017/11/14

Y1 - 2017/11/14

N2 - In the present study we describe the synthesis, photophysical properties and the photoinactivation performance against representative microorganisms of two families of cationic dendrimeric phthalocyanines as potential photosensitisers. Four charged dendrimeric compounds varying in their degree of ionicity (4 or 8 positive charges) and the coordinating metal (zinc or ruthenium) are compared and assessed as potential photosensitising agents in terms of their antimicrobial activity.

AB - In the present study we describe the synthesis, photophysical properties and the photoinactivation performance against representative microorganisms of two families of cationic dendrimeric phthalocyanines as potential photosensitisers. Four charged dendrimeric compounds varying in their degree of ionicity (4 or 8 positive charges) and the coordinating metal (zinc or ruthenium) are compared and assessed as potential photosensitising agents in terms of their antimicrobial activity.

KW - Photophysical properties

KW - Efficient photosensitizers

KW - Photodynamic inactivation

KW - Antibiotics

KW - Porphyrins

KW - Resistance

KW - Therapy

KW - Photoinactivation

KW - Porphycenes

KW - Infections

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JO - Organic and Biomolecular Chemistry

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ER -

Cationic phthalocyanine dendrimers as potential antimicrobial photosensitisers

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