Resumen
Protein therapeutics cannot reach the brain in sufficient amounts because of their low permeability across the blood-brain barrier. Here we report a new family of bicyclic peptide shuttles, BrainBikes, capable of increasing transport of proteins, including antibody derivatives, in a human cell-based model of the blood-brain barrier.
Idioma original | Inglés |
---|---|
Páginas (desde-hasta) | 7-11 |
Número de páginas | 5 |
Publicación | RSC Chemical Biology |
Volumen | 5 |
N.º | 1 |
DOI | |
Estado | Publicada - ene 2024 |