TY - JOUR
T1 - Advanced oxidation of the antibiotic sulfapyridine by UV/H2O2
T2 - Characterization of its transformation products and ecotoxicological implications
AU - García-Galán, Ma Jesús
AU - Anfruns, Alba
AU - Gonzalez-Olmos, Rafael
AU - Rodriguez-Mozaz, Sara
AU - Comas, Joaquim
N1 - Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2016/3
Y1 - 2016/3
N2 - The aim of the present work is to investigate, under lab-scale conditions, the removal and transformation of the antibiotic sulfapyridine (SPY) upon advanced oxidation with UV/H2O2. High resolution mass spectrometry (HRMS) analyses by means of an ultra-high pressure liquid chromatography (UHPLC)-linear ion trap high resolution Orbitrap instrument (LTQ-Orbitrap-MS) were carried out in order to elucidate the different transformation products (TPs) generated. The abatement (>99%) of the antibiotic was only achieved after 180 min, highlighting its resilience to elimination and its potential persistence in the environment A total of 10 TPs for SPY were detected and their molecular structures elucidated by means of MS2 and MS3 scans. Finally, the combined ecotoxicity at different treatment times was evaluated by means of bioluminescence inhibition assays with the marine bacteria Vibrio fischeri.
AB - The aim of the present work is to investigate, under lab-scale conditions, the removal and transformation of the antibiotic sulfapyridine (SPY) upon advanced oxidation with UV/H2O2. High resolution mass spectrometry (HRMS) analyses by means of an ultra-high pressure liquid chromatography (UHPLC)-linear ion trap high resolution Orbitrap instrument (LTQ-Orbitrap-MS) were carried out in order to elucidate the different transformation products (TPs) generated. The abatement (>99%) of the antibiotic was only achieved after 180 min, highlighting its resilience to elimination and its potential persistence in the environment A total of 10 TPs for SPY were detected and their molecular structures elucidated by means of MS2 and MS3 scans. Finally, the combined ecotoxicity at different treatment times was evaluated by means of bioluminescence inhibition assays with the marine bacteria Vibrio fischeri.
KW - Ecotoxicity
KW - Metabolite
KW - Sulfapyridine
KW - Transformation products
KW - UV/HO oxidation
UR - http://www.scopus.com/inward/record.url?scp=84957809775&partnerID=8YFLogxK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:000370836100058&DestLinkType=FullRecord&DestApp=WOS_CPL
U2 - 10.1016/j.chemosphere.2015.12.108
DO - 10.1016/j.chemosphere.2015.12.108
M3 - Article
C2 - 26789837
AN - SCOPUS:84957809775
SN - 0045-6535
VL - 147
SP - 451
EP - 459
JO - Chemosphere
JF - Chemosphere
ER -
