Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

Pedro Victory; JoséI I. Borrell; Anton Vidal-Ferran; Elvira Montenegro; M. Luisa Jimeno

doi:10.3987/com-93-6412

Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

Pedro Victory^*
, JoséI I. Borrell
, Anton Vidal-Ferran
, Elvira Montenegro
, M. Luisa Jimeno

^*Corresponding author for this work

Research output: Indexed journal article › Article › peer-review

25 Citations (Scopus)

Abstract

The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.

Original language	English
Pages (from-to)	2273-2280
Number of pages	8
Journal	Heterocycles
Volume	36
Issue number	10
DOIs	https://doi.org/10.3987/com-93-6412
Publication status	Published - 1 Oct 1993

Access to Document

10.3987/com-93-6412

Cite this

@article{ba206c7d93244458b1f5a766922a0de2,

title = "Synthesis of 4-amino-8-cyanoquinazolines from enones and enals",

abstract = "The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.",

author = "Pedro Victory and Borrell, \{Jos{\'e}I I.\} and Anton Vidal-Ferran and Elvira Montenegro and Jimeno, \{M. Luisa\}",

year = "1993",

month = oct,

day = "1",

doi = "10.3987/com-93-6412",

language = "English",

volume = "36",

pages = "2273--2280",

journal = "Heterocycles",

issn = "0385-5414",

publisher = "Japan Institute of Heterocyclic Chemistry",

number = "10",

}

TY - JOUR

T1 - Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

AU - Victory, Pedro

AU - Borrell, JoséI I.

AU - Vidal-Ferran, Anton

AU - Montenegro, Elvira

AU - Jimeno, M. Luisa

PY - 1993/10/1

Y1 - 1993/10/1

N2 - The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.

AB - The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.

UR - https://www.scopus.com/pages/publications/0001503216

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:A1993LY45000016&DestLinkType=FullRecord&DestApp=WOS_CPL

U2 - 10.3987/com-93-6412

DO - 10.3987/com-93-6412

M3 - Article

AN - SCOPUS:0001503216

SN - 0385-5414

VL - 36

SP - 2273

EP - 2280

JO - Heterocycles

JF - Heterocycles

IS - 10

ER -

Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

Abstract

Access to Document

Other files and links

Fingerprint

Cite this