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Silica-based nanosystems for therapeutic applications in the skin

  • Francisco Arriagada*
  • , Santi Nonell
  • , Javier Morales
  • *Corresponding author for this work

Research output: Indexed journal article Reviewpeer-review

30 Citations (Scopus)

Abstract

Aging, exposure to oxidants, infectious pathogens, inflammogens, ultraviolet radiation and other environmental and genetic factors can result in the development of various skin disorders. Despite immense progress being made in dermatological treatments, many skin-associated problems still remain difficult to treat and various therapies have limitations. Progress in silica-based nanomaterials research provides an opportunity to overcome these drawbacks and improve therapies and is a promising tool for inclusion in clinical practice to treat skin diseases. This review focuses on the use of various types of silica nanoparticles with therapeutic applications in various skin disorders. These nanosystems improve treatment efficacy by maintaining or enhancing the effect of several drugs and are useful tools for nanomedicine, pharmaceutical sciences and future clinical applications.

Original languageEnglish
Pages (from-to)2243-2267
Number of pages25
JournalNanomedicine
Volume14
Issue number16
DOIs
Publication statusPublished - Aug 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • cancer
  • nanomedicine
  • photodynamic therapy
  • photoprotection
  • silica nanoparticles
  • silica nanosystems
  • skin
  • skin disorders
  • topical delivery
  • wound healing

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