Semiparametric modeling for the cardiometabolic risk index and individual risk factors in the older adult population: A novel proposal

Philippe Tagder, Margareth Lorena Alfonso-Mora, Diana Díaz-Vidal, Aura Cristina Quino-Ávila, Juliana Lever Méndez, Carolina Sandoval-Cuellar, Eliana Monsalve-Jaramillo, María Giné-Garriga

Research output: Indexed journal article Articlepeer-review

Abstract

The accurate monitoring of metabolic syndrome in older adults is relevant in terms of its early detection, and its management. This study aimed at proposing a novel semiparametric modeling for a cardiometabolic risk index (CMRI) and individual risk factors in older adults. Methods: Multivariate semiparametric regression models were used to study the association between the CMRI with the individual risk factors, which was achieved using secondary analysis the data from the SABE study (Survey on Health, Well-Being, and Aging in Colombia, 2015). Results: The risk factors were selected through a stepwise procedure. The covariates included showed evidence of non-linear relationships with the CMRI, revealing non-linear interactions between: BMI and age (p< 0.00); arm and calf circumferences (p<0.00); age and females (p<0.00); walking speed and joint pain (p<0.02); and arm circumference and joint pain (p<0.00). Conclusions: Semiparametric modeling explained 24.5% of the observed deviance, which was higher than the 18.2% explained by the linear model.

Original languageEnglish
Article numbere0299032
JournalPLOS ONE
Volume19
Issue number4 April
DOIs
Publication statusPublished - Apr 2024

Fingerprint

Dive into the research topics of 'Semiparametric modeling for the cardiometabolic risk index and individual risk factors in the older adult population: A novel proposal'. Together they form a unique fingerprint.

Cite this