TY - JOUR
T1 - Relationship between olive oil consumption and ankle-brachial pressure index in a population at high cardiovascular risk
AU - Sánchez-Quesada, Cristina
AU - Toledo, Estefanía
AU - González-Mata, Guadalupe
AU - Ramos-Ballesta, Maria Isabel
AU - Peis, José Ignacio
AU - Martínez-González, Miguel Ángel
AU - Salas-Salvadó, Jordi
AU - Corella, Dolores
AU - Fitó, Montserrat
AU - Romaguera, Dora
AU - Vioque, Jesús
AU - Alonso-Gómez, Ángel M.
AU - Wärnberg, Julia
AU - Martínez, J. Alfredo
AU - Serra-Majem, Luís
AU - Estruch, Ramon
AU - Tinahones, Francisco J.
AU - Lapetra, José
AU - Pintó, Xavier
AU - Tur, Josep A.
AU - Garcia-Rios, Antonio
AU - Cano-Ibáñez, Naomi
AU - Matía-Martín, Pilar
AU - Daimiel, Lidia
AU - Sánchez-Rodríguez, Rubén
AU - Vidal, Josep
AU - Vázquez, Clotilde
AU - Ros, Emilio
AU - Hernández-Alonso, Pablo
AU - Barragan, Rocío
AU - Muñoz-Martínez, Julia
AU - López, Meritxell
AU - González-Palacios, Sandra
AU - Vaquero-Luna, Jessica
AU - Crespo-Oliva, Edelys
AU - Zulet, M. Angeles
AU - Díaz-González, Vanessa
AU - Casas, Rosa
AU - Fernandez-Garcia, José Carlos
AU - Santos-Lozano, José Manuel
AU - Galera, Ana
AU - Ripoll-Vera, Tomás
AU - Buil-Cosiales, Pilar
AU - Canudas, Silvia
AU - Martinez-Lacruz, Raul
AU - Pérez-Vega, Karla Alejandra
AU - Rios, Ángel
AU - Lloret-Macián, Rosario
AU - Moreno-Rodriguez, Anai
AU - Ruiz-Canela, Miguel
AU - Babio, Nancy
AU - Zomeño Fajardo, Maria Dolores
AU - Gaforio, José J.
N1 - Funding Information:
Dr Estruch reported receiving grants from Instituto de Salud Carlos III and olive oil for the trial from Fundacion Patrimonio Comunal Olivarero during the conduct of the study and personal fees from Brewers of Europe, Fundación Cerveza y Salud, Interprofesional del Aceite de Oliva, Instituto Cervantes, Instituto Cervantes, Pernaud Richar, Fundación Dieta Mediterránea, Wine and Culinary International Forum; nonfinancial support from Sociedad Española de Nutrición and Fundación Bosch y Gimpera; and grants from Uriach Laboratories outside the submitted work.
Funding Information:
The PREDIMED-Plus trial was supported by the official funding agency for biomedical research of the Spanish government, ISCIII , through the Fondo de Investigación para la Salud (FIS) , which is co-funded by the European Regional Development Fund (five coordinated FIS projects led by J.S.-S. and J.Vid., including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, and PI19/01332), the Especial Action Project entitled: Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-Plus grant to J.S.-S., the European Research Council (Advanced Research Grant 2013–2018, 340918 ) to M.Á.M.-G., the Recercaixa Grant to J.S.-S. ( 2013ACUP00194 ), a grant from the Generalitat Valenciana ( APOSTD/2019/136 to RB), grants from the Consejería de Salud de la Junta de Andalucía ( PI0458/2013 , PS0358/2016 , and PI0137/2018 ), a grant from the Generalitat Valenciana ( PROMETEO/2017/017 ), a SEMERGEN Grant, EU-COST Action CA16112 , a grant of support to research groups no. 35/2011 from the Balearic Islands Government , Grants from Balearic Islands Health Research Institute (IDISBA) , funds from the European Regional Development Fund (CIBEROBN CB06/03 and CB12/03 ) and from the European Commission ( EAT2BENICE_H2020_SFS2016 ). PH-A is supported by a postdoctoral fellowship ( Juan de la Cierva-Formación , FJCI-2017-32205 ). GG-M is supported by a grant of Diputación de Jaén . The funding sponsors had no role in the design of the study, in the collection, analyses, or interpretation of the data; in the writing of the manuscript, and in the decision to publish the results.
Funding Information:
The PREDIMED-Plus trial was supported by the official funding agency for biomedical research of the Spanish government, ISCIII, through the Fondo de Investigaci?n para la Salud (FIS), which is co-funded by the European Regional Development Fund (five coordinated FIS projects led by J.S.-S. and J.Vid., including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, and PI19/01332), the Especial Action Project entitled: Implementaci?n y evaluaci?n de una intervenci?n intensiva sobre la actividad f?sica Cohorte PREDIMED-Plus grant to J.S.-S., the European Research Council (Advanced Research Grant 2013?2018, 340918) to M.?.M.-G., the Recercaixa Grant to J.S.-S. (2013ACUP00194), a grant from the Generalitat Valenciana (APOSTD/2019/136 to RB), grants from the Consejer?a de Salud de la Junta de Andaluc?a (PI0458/2013, PS0358/2016, and PI0137/2018), a grant from the Generalitat Valenciana (PROMETEO/2017/017), a SEMERGEN Grant, EU-COST Action CA16112, a grant of support to research groups no. 35/2011 from the Balearic Islands Government, Grants from Balearic Islands Health Research Institute (IDISBA), funds from the European Regional Development Fund (CIBEROBN CB06/03 and CB12/03) and from the European Commission (EAT2BENICE_H2020_SFS2016). PH-A is supported by a postdoctoral fellowship (Juan de la Cierva-Formaci?n, FJCI-2017-32205). GG-M is supported by a grant of Diputaci?n de Ja?n. The funding sponsors had no role in the design of the study, in the collection, analyses, or interpretation of the data; in the writing of the manuscript, and in the decision to publish the results.Dr Estruch reported receiving grants from Instituto de Salud Carlos III and olive oil for the trial from Fundacion Patrimonio Comunal Olivarero during the conduct of the study and personal fees from Brewers of Europe, Fundaci?n Cerveza y Salud, Interprofesional del Aceite de Oliva, Instituto Cervantes, Instituto Cervantes, Pernaud Richar, Fundaci?n Dieta Mediterr?nea, Wine and Culinary International Forum; nonfinancial support from Sociedad Espa?ola de Nutrici?n and Fundaci?n Bosch y Gimpera; and grants from Uriach Laboratories outside the submitted work.
Funding Information:
Jordi Salas-Salvadó reports serving on the board of the International Nut and Dried Fruit Council, the Danone International Institute, and the Eroski Foundation and receiving grant support from these entities through his institution. He also reports serving on the Executive Committee of the Instituto Danone Spain. He has also received the olive oil and nuts used in PREDIMED and PREDIMED-plus studies from the Patrimonio Comunal Olivarero, Spain; La Morella Nuts, Spain; and Borges S.A., Spain. He reports receiving consulting fees or travel expenses from Danone; the California Walnut Commission, the Eroski Foundation, the Instituto Danone - Spain, Nuts for Life, the Australian Nut Industry Council, Nestlé, Abbot Laboratories, and Font Vella Lanjarón.
Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2020/12
Y1 - 2020/12
N2 - Background and aims: The aim of this study was to ascertain the association between the consumption of different categories of edible olive oils (virgin olive oils and olive oil) and olive pomace oil and ankle-brachial pressure index (ABI) in participants in the PREDIMED-Plus study, a trial of lifestyle modification for weight and cardiovascular event reduction in individuals with overweight/obesity harboring the metabolic syndrome. Methods: We performed a cross-sectional analysis of the PREDIMED-Plus trial. Consumption of any category of olive oil and olive pomace oil was assessed through a validated food-frequency questionnaire. Multivariable linear regression models were fitted to assess associations between olive oil consumption and ABI. Additionally, ABI ≤1 was considered as the outcome in logistic models with different categories of olive oil and olive pomace oil as exposure. Results: Among 4330 participants, the highest quintile of total olive oil consumption (sum of all categories of olive oil and olive pomace oil) was associated with higher mean values of ABI (beta coefficient: 0.014, 95% confidence interval [CI]: 0.002, 0.027) (p for trend = 0.010). Logistic models comparing the consumption of different categories of olive oils, olive pomace oil and ABI ≤1 values revealed an inverse association between virgin olive oils consumption and the likelihood of a low ABI (odds ratio [OR] 0.73, 95% CI [0.56, 0.97]), while consumption of olive pomace oil was positively associated with a low ABI (OR 1.22 95% CI [1.00, 1.48]). Conclusions: In a Mediterranean population at high cardiovascular risk, total olive oil consumption was associated with a higher mean ABI. These results suggest that olive oil consumption may be beneficial for peripheral artery disease prevention, but longitudinal studies are needed.
AB - Background and aims: The aim of this study was to ascertain the association between the consumption of different categories of edible olive oils (virgin olive oils and olive oil) and olive pomace oil and ankle-brachial pressure index (ABI) in participants in the PREDIMED-Plus study, a trial of lifestyle modification for weight and cardiovascular event reduction in individuals with overweight/obesity harboring the metabolic syndrome. Methods: We performed a cross-sectional analysis of the PREDIMED-Plus trial. Consumption of any category of olive oil and olive pomace oil was assessed through a validated food-frequency questionnaire. Multivariable linear regression models were fitted to assess associations between olive oil consumption and ABI. Additionally, ABI ≤1 was considered as the outcome in logistic models with different categories of olive oil and olive pomace oil as exposure. Results: Among 4330 participants, the highest quintile of total olive oil consumption (sum of all categories of olive oil and olive pomace oil) was associated with higher mean values of ABI (beta coefficient: 0.014, 95% confidence interval [CI]: 0.002, 0.027) (p for trend = 0.010). Logistic models comparing the consumption of different categories of olive oils, olive pomace oil and ABI ≤1 values revealed an inverse association between virgin olive oils consumption and the likelihood of a low ABI (odds ratio [OR] 0.73, 95% CI [0.56, 0.97]), while consumption of olive pomace oil was positively associated with a low ABI (OR 1.22 95% CI [1.00, 1.48]). Conclusions: In a Mediterranean population at high cardiovascular risk, total olive oil consumption was associated with a higher mean ABI. These results suggest that olive oil consumption may be beneficial for peripheral artery disease prevention, but longitudinal studies are needed.
KW - Ankle-brachial pressure index
KW - Olive oil
KW - Olive pomace oil
KW - Peripheral artery disease
KW - PREDIMED-Plus trial
KW - Virgin olive oils
UR - https://www.scopus.com/pages/publications/85095459060
UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000591758300007
U2 - 10.1016/j.atherosclerosis.2020.10.008
DO - 10.1016/j.atherosclerosis.2020.10.008
M3 - Article
C2 - 33160246
AN - SCOPUS:85095459060
SN - 0021-9150
VL - 314
SP - 48
EP - 57
JO - Atherosclerosis
JF - Atherosclerosis
ER -
SDG 3 Good Health and Well-being