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Potential Applications of Cucurbit[n]urils Inclusion Complexes in Photodynamic Therapy

  • José Robinson-Duggon
  • , Francisco Pérez-Mora
  • , Luciano Dibona-Villanueva
  • , Denis Fuentealba*
  • *Corresponding author for this work

Research output: Indexed journal article Reviewpeer-review

30 Citations (Scopus)

Abstract

Cucurbit[n]urils (CB[n]s) have emerged as potential candidates for drug delivery in several areas due to their strong binding interactions and low toxicity. More recently, their benefits for a type of cancer treatment termed Photodynamic Therapy (PDT) have been recognized. The outcomes of this therapy rely on better drug delivery strategies and improving overall photoactivity of the drugs, which is where CB[n]s could have a strong impact. The effects of these molecular containers on photoactivity are discussed and new interesting work is highlighted.

Original languageEnglish
Pages (from-to)199-214
Number of pages16
JournalIsrael Journal of Chemistry
Volume58
Issue number3
DOIs
Publication statusPublished - Apr 2018
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • cucurbit[n]uril
  • inclusion complex
  • Photodynamic therapy
  • photosensitizer
  • singlet oxygen

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