Photosensitisers for photodynamic therapy: State of the art and perspectives

Beatriz Rodríguez Amigo; Oriol Planas Marques; Roger Bresoli Obach; Joaquim Torra Nonell; Ruben Ruiz Gonzalez; Santiago Nonell Marrugat

doi:10.1039/9781782626824-00023

Photosensitisers for photodynamic therapy: State of the art and perspectives

Beatriz Rodríguez Amigo
, Oriol Planas Marques
, Roger Bresoli Obach
, Joaquim Torra Nonell
, Ruben Ruiz Gonzalez
, Santiago Nonell Marrugat

Research output: Book chapter › Chapter

7 Citations (Web of Science)

Abstract

Photodynamic therapy relies on the action of a photosensitising drug in order to generate reactive oxygen species that cause damage to biological cells and tissues. The key aspects for the success of this therapy are the optical and photosensitising properties of the drug, as well as its pharmacological properties. This chapter provides an overview of the drugs already approved for clinical use for cancer, antimicrobial or other applications, as well as a list of those in clinical trials and at the preclinical stage. Emerging strategies for controlling the production of reactive oxygen species and novel photosensitising modalities brought about by the bio- and nano-revolutions are discussed.

Translated title of the contribution	Photosensitisers for photodynamic therapy: State of the art and perspectives
Original language	English
Title of host publication	Photodynamic Medicine: From bench to clinic
Editors	Herwig Kostron, Tayyaba Hasan
Publisher	Royal Society of Chemistry
Chapter	2
Pages	23-62
Number of pages	39
ISBN (Electronic)	978-1-78262-823-1, 978-1-78262-682-4
ISBN (Print)	978-1-78262-451-6
DOIs	https://doi.org/10.1039/9781782626824-00023
Publication status	Published - 2016

Publication series

Name	Comprehensive Series in Photochemical & Photobiological Sciences
ISSN (Print)	2041-9716
ISSN (Electronic)	2041-9724

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Singlet-oxygen generation
Near-infrared photoimmunotherapy
Aggregation-induced emission
Walled carbon nanotubes
Genetically-encoded photosensitizer
Targeting cancer-cells
Collagen cross-linking
Growth-factor receptor
Icg laser therapy
Fluorescent protein

Access to Document

10.1039/9781782626824-00023

Cite this

Rodríguez Amigo, B., Planas Marques, O., Bresoli Obach, R., Torra Nonell, J., Ruiz Gonzalez, R., & Nonell Marrugat, S. (2016). Photosensitisers for photodynamic therapy: State of the art and perspectives. In H. Kostron, & T. Hasan (Eds.), Photodynamic Medicine: From bench to clinic (pp. 23-62). (Comprehensive Series in Photochemical & Photobiological Sciences). Royal Society of Chemistry. https://doi.org/10.1039/9781782626824-00023

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title = "Photosensitisers for photodynamic therapy: State of the art and perspectives",

abstract = "Photodynamic therapy relies on the action of a photosensitising drug in order to generate reactive oxygen species that cause damage to biological cells and tissues. The key aspects for the success of this therapy are the optical and photosensitising properties of the drug, as well as its pharmacological properties. This chapter provides an overview of the drugs already approved for clinical use for cancer, antimicrobial or other applications, as well as a list of those in clinical trials and at the preclinical stage. Emerging strategies for controlling the production of reactive oxygen species and novel photosensitising modalities brought about by the bio- and nano-revolutions are discussed.",

keywords = "Singlet-oxygen generation, Near-infrared photoimmunotherapy, Aggregation-induced emission, Walled carbon nanotubes, Genetically-encoded photosensitizer, Targeting cancer-cells, Collagen cross-linking, Growth-factor receptor, Icg laser therapy, Fluorescent protein",

author = "\{Rodr{\'i}guez Amigo\}, Beatriz and \{Planas Marques\}, Oriol and \{Bresoli Obach\}, Roger and \{Torra Nonell\}, Joaquim and \{Ruiz Gonzalez\}, Ruben and \{Nonell Marrugat\}, Santiago",

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doi = "10.1039/9781782626824-00023",

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isbn = "978-1-78262-451-6",

series = "Comprehensive Series in Photochemical \& Photobiological Sciences",

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booktitle = "Photodynamic Medicine: From bench to clinic",

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Rodríguez Amigo, B, Planas Marques, O, Bresoli Obach, R, Torra Nonell, J, Ruiz Gonzalez, R & Nonell Marrugat, S 2016, Photosensitisers for photodynamic therapy: State of the art and perspectives. in H Kostron & T Hasan (eds), Photodynamic Medicine: From bench to clinic. Comprehensive Series in Photochemical & Photobiological Sciences, Royal Society of Chemistry, pp. 23-62. https://doi.org/10.1039/9781782626824-00023

Photosensitisers for photodynamic therapy: State of the art and perspectives. / Rodríguez Amigo, Beatriz; Planas Marques, Oriol; Bresoli Obach, Roger et al.
Photodynamic Medicine: From bench to clinic. ed. / Herwig Kostron; Tayyaba Hasan. Royal Society of Chemistry, 2016. p. 23-62 (Comprehensive Series in Photochemical & Photobiological Sciences).

Research output: Book chapter › Chapter

TY - CHAP

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AU - Rodríguez Amigo, Beatriz

AU - Planas Marques, Oriol

AU - Bresoli Obach, Roger

AU - Torra Nonell, Joaquim

AU - Ruiz Gonzalez, Ruben

AU - Nonell Marrugat, Santiago

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KW - Aggregation-induced emission

KW - Walled carbon nanotubes

KW - Genetically-encoded photosensitizer

KW - Targeting cancer-cells

KW - Collagen cross-linking

KW - Growth-factor receptor

KW - Icg laser therapy

KW - Fluorescent protein

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ER -

Rodríguez Amigo B, Planas Marques O, Bresoli Obach R, Torra Nonell J, Ruiz Gonzalez R, Nonell Marrugat S. Photosensitisers for photodynamic therapy: State of the art and perspectives. In Kostron H, Hasan T, editors, Photodynamic Medicine: From bench to clinic. Royal Society of Chemistry. 2016. p. 23-62. (Comprehensive Series in Photochemical & Photobiological Sciences). doi: 10.1039/9781782626824-00023

Photosensitisers for photodynamic therapy: State of the art and perspectives

Abstract

Publication series

UN SDGs

Keywords

Access to Document

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