Photodynamic Therapy

Cormac Hally, Beatriz Rodríguez Amigo, Roger Bresoli Obach, Oriol Planas, Jaime Nos Aguila, Ester Boix-Garriga, Ruben Ruiz Gonzalez, Santiago Nonell Marrugat

Research output: Book chapterChapter

Abstract

Photodynamic therapy is a clinical technique for the treatment of cancers, microbial infections and other medical conditions by means of light-induced generation of reactive oxygen species using photosensitising drugs. The intrinsic fluorescence of many such drugs make them potential theranostic agents for simultaneous diagnosis and therapy. This chapter reviews the basic chemical and biological aspects of photodynamic therapy with an emphasis on its applications in theranostics. The roles of nanotechnology is highlighted, as well as emerging trends such as photoimmunotherapy, image-guided surgery and light- and singlet-oxygen dosimetry.
Translated title of the contributionPhotodynamic Therapy: Theranostics and Image Guided Drug Delivery, edited by Maya Thanou
Original languageEnglish
Title of host publicationTheranostics and Image Guided Drug Delivery
EditorsMaya Thanou
PublisherRoyal Society of Chemistry
Chapter4
Pages86-122
ISBN (Electronic)978-1-78801-393-2
ISBN (Print)978-1-78262-466-0
DOIs
Publication statusPublished - Jan 2018

Publication series

NameDrug Discovery
ISSN (Print)2041-3203
ISSN (Electronic)2041-3211

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