Abstract
An easy access to highly versatile gem-silylboronate synthons is achieved by means of a new olefination reagent, HC(Bpin)2(SiMe3). Subsequent silicon or boron-based selective functionalization allows for the modular and stereocontrolled synthesis of all-carbon tetrasubstituted alkenes. A particular attraction of this approach is the iododesilylation reaction, which becomes a pivotal tool for C−Si functionalization.
Original language | English |
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Pages (from-to) | 18737-18741 |
Number of pages | 5 |
Journal | Chemistry - A European Journal |
Volume | 22 |
Issue number | 52 |
DOIs | |
Publication status | Published - 23 Dec 2016 |
Externally published | Yes |
Keywords
- alkenes
- gem-silylborylation
- insertion
- iododesilylation
- tamoxifen