Newest approaches to singlet oxygen photosensitisation in biological media

Oriol Planas, Ester Boix-Garriga, Beatriz Rodríguez-Amigo, Joaquim Torra, Roger Bresolí-Obach, Cristina Flors, Cristiano Viappiani, Montserrat Agut, Rubén Ruiz-González, Santi Nonell*

*Corresponding author for this work

Research output: Book chapterChapterpeer-review

24 Citations (Web of Science)

Abstract

Production of singlet molecular oxygen by photosensitisation remains the most common and convenient means of producing this non-radical yet highly-reactive oxygen species that participates in many chemical and biological processes. The details of singlet oxygen photosensitisation by organic dyes are well understood as well as its limitations. Novel materials and biomaterials with unprecedented optical, photophysical, and biological properties, as well as novel chemical and biological technologies have recently emerged that provide new opportunities for the controlled generation and delivery of singlet oxygen in biological media as well as for its detection and monitoring. This review summarises such novel contributions, ranging from stimulus-responsive switchable molecular photosensitisers to proteins as novel photoactive biotherapeutic drugs to metallic nanostructures as plasmonic antennas for singlet oxygen.

Original languageEnglish
Title of host publicationPhotochemistry
EditorsElisa Fasani, Angelo Albini
PublisherRoyal Society of Chemistry
Pages233-278
Number of pages46
ISBN (Electronic)978-1-78262-454-7
ISBN (Print)978-1-84973-956-6
DOIs
Publication statusPublished - 2015

Publication series

NamePhotochemistry
Volume42
ISSN (Print)0556-3860

Keywords

  • Photodynamic molecular beacon
  • Walled carbon nanotubes
  • Growth-factor receptor
  • Genetically-encoded photosensitizer
  • Semiconductor quantum dots
  • Air-saturated solutions
  • Rose-bengal acetate
  • Nm laser-radiation
  • Fluorescent protein
  • Porous silicon

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