Modification of carbon nanotubes for gene delivery vectors

Victor Ramos-Perez, Anna Cifuentes, Núria Coronas, Ana De Pablo, Salvador Borrós

Research output: Book chapterChapterpeer-review

25 Citations (Scopus)

Abstract

The surface modification of carbon nanotubes (CNTs) can be tailored to allow the formation of a complex between these potential carriers with DNA. In this chapter, protocols developed in our lab to prepare transfection vectors through the modification of MWCNTs are described. The protocol includes sections focused on the reduction of CNTs length, protocols to increase the dispersability of CNTs and finally, protocols for surface modification to attach through electrostatic interactions DNA to the CNTs.

Original languageEnglish
Title of host publicationNanomaterial Interfaces in Biology
Subtitle of host publicationMethods and Protocols
PublisherHumana Press Inc.
Pages261-268
Number of pages8
ISBN (Print)9781627034616
DOIs
Publication statusPublished - 2013

Publication series

NameMethods in Molecular Biology
Volume1025
ISSN (Print)1064-3745

Keywords

  • Carbon nanotubes
  • DNA delivery
  • Plasma polymerization

Fingerprint

Dive into the research topics of 'Modification of carbon nanotubes for gene delivery vectors'. Together they form a unique fingerprint.

Cite this