TY - JOUR
T1 - Mechanisms of hypoxaemia in severe pulmonary hypertension associated with COPD
AU - Piccari, Lucilla
AU - Blanco, Isabel
AU - Torralba, Yolanda
AU - Arismendi, Ebymar
AU - Gistau, Concepción
AU - Ramírez, Ana
AU - Gimeno-Santos, Elena
AU - Roca, Josep
AU - Burgos, Felip
AU - Rodríguez-Roisín, Roberto
AU - Barberà, Joan Albert
N1 - Lucilla Piccari1, Isabel Blanco1,2,3⇑, Yolanda Torralba1,2,3, Ebymar Arismendi1,2,3, Concepción Gistau1, Ana Ramírez1, Elena Gimeno-Santos1,2, Josep Roca1,2,3, Felip Burgos1,2,3, Roberto Rodríguez-Roisín1,2,3 and Joan Albert Barberà1,2,3.
Copyright ©Theauthors 2023.
Funding sponsors: Instituto de Salud Carlos III, Sociedad Española de Neumología y Cirugía Torácica, European Regional Development Fund, Societat Catalana de Pneumologia.
Conflict of interest: L. Piccari reports grants and lecture honoraria from Janssen and Ferrer, participation on advisory boards with Janssen, Ferrer and United Therapeutics, and travel support from Janssen, Ferrer and MSD, outside the submitted work. I. Blanco reports lecture honoraria from Janssen, MSD and Ferrer, outside the submitted work. Y. Torralba reports lecture honoraria from TEVA, outside the submitted work. F. Burgos reports consulting fees for participation in a scientific advisory board for Medical Graphics Diagnostics, outside the submitted work. R. Rodríguez-Roisín reports grants from Chiesi Spain, outside the submitted work. J.A. Barberà reports consulting fees from Merck Sharp & Dome, Janssen-Cilag and Acceleron Pharma, lecture honoraria from Ferrer International, Janssen-Cilag and Merck Sharp & Dome, and travel support from Merck Sharp & Dome and Janssen-Cilag, outside the submitted work. All other authors have nothing to disclose.
PY - 2023/7/1
Y1 - 2023/7/1
N2 - Severe hypoxaemia, characteristic of COPD with severe pulmonary hypertension, is due to a combination of greater ventilation–perfusion mismatch, increased intrapulmonary shunt and reduced PvO2, with negligible hypoxic pulmonary vasoconstriction regulation
AB - Severe hypoxaemia, characteristic of COPD with severe pulmonary hypertension, is due to a combination of greater ventilation–perfusion mismatch, increased intrapulmonary shunt and reduced PvO2, with negligible hypoxic pulmonary vasoconstriction regulation
KW - COPD
KW - Pulmonary hypertension
KW - Hypoxaemia
UR - http://www.scopus.com/inward/record.url?scp=85165521604&partnerID=8YFLogxK
UR - https://www.webofscience.com/wos/alldb/full-record/WOS:001041262200006
U2 - 10.1183/13993003.00463-2023
DO - 10.1183/13993003.00463-2023
M3 - Letter
C2 - 37414421
AN - SCOPUS:85165521604
SN - 0903-1936
VL - 62
SP - 1
EP - 5
JO - European Respiratory Journal
JF - European Respiratory Journal
IS - 1
M1 - 2300463
ER -