Light- and singlet oxygen-mediated antifungal activity of phenylphenalenone phytoalexins

Alejandra Lazzaro; Montserrat Corominas; Cristina Martí; Cristina Flors; Laura R. Izquierdo; Teresa A. Grillo; Javier G. Luis; Santi Nonell

doi:10.1039/b401294a

Light- and singlet oxygen-mediated antifungal activity of phenylphenalenone phytoalexins

Alejandra Lazzaro
, Montserrat Corominas
, Cristina Martí
, Cristina Flors
, Laura R. Izquierdo
, Teresa A. Grillo
, Javier G. Luis
, Santi Nonell^*

^*Corresponding author for this work

Research output: Indexed journal article › Article › peer-review

57 Citations (Scopus)

Abstract

The light-induced singlet oxygen production and antifungal activity of phenylphenalenone phytoalexins isolated from infected banana plants (Musa acuminata) are reported. Upon absorption of light energy all studied phenylphenalenones sensitise the production of singlet oxygen in polar and non-polar media. Antifungal activity of these compounds towards Fusarium oxysporum is enhanced in the presence of light. These results, together with the correlation of IC₅₀ values under illumination with the quantum yield of singlet oxygen production and the enhancing effect of D₂O on the antifungal activity, suggest the intermediacy of singlet oxygen produced by electronic excitation of the phenylphenalenone phytoalexins.

Original language	English
Pages (from-to)	706-710
Number of pages	5
Journal	Photochemical and Photobiological Sciences
Volume	3
Issue number	7
DOIs	https://doi.org/10.1039/b401294a
Publication status	Published - 6 Jul 2004

Keywords

Phenalenone-type phytoalexins
Musa-acuminata
Natural-products
Resistance
Deactivation
Accumulation
Generation
Defense
Plants
Yields

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10.1039/b401294a

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title = "Light- and singlet oxygen-mediated antifungal activity of phenylphenalenone phytoalexins",

abstract = "The light-induced singlet oxygen production and antifungal activity of phenylphenalenone phytoalexins isolated from infected banana plants (Musa acuminata) are reported. Upon absorption of light energy all studied phenylphenalenones sensitise the production of singlet oxygen in polar and non-polar media. Antifungal activity of these compounds towards Fusarium oxysporum is enhanced in the presence of light. These results, together with the correlation of IC50 values under illumination with the quantum yield of singlet oxygen production and the enhancing effect of D2O on the antifungal activity, suggest the intermediacy of singlet oxygen produced by electronic excitation of the phenylphenalenone phytoalexins.",

keywords = "Phenalenone-type phytoalexins, Musa-acuminata, Natural-products, Resistance, Deactivation, Accumulation, Generation, Defense, Plants, Yields",

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doi = "10.1039/b401294a",

language = "English",

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T1 - Light- and singlet oxygen-mediated antifungal activity of phenylphenalenone phytoalexins

AU - Lazzaro, Alejandra

AU - Corominas, Montserrat

AU - Martí, Cristina

AU - Flors, Cristina

AU - Izquierdo, Laura R.

AU - Grillo, Teresa A.

AU - Luis, Javier G.

AU - Nonell, Santi

PY - 2004/7/6

Y1 - 2004/7/6

N2 - The light-induced singlet oxygen production and antifungal activity of phenylphenalenone phytoalexins isolated from infected banana plants (Musa acuminata) are reported. Upon absorption of light energy all studied phenylphenalenones sensitise the production of singlet oxygen in polar and non-polar media. Antifungal activity of these compounds towards Fusarium oxysporum is enhanced in the presence of light. These results, together with the correlation of IC50 values under illumination with the quantum yield of singlet oxygen production and the enhancing effect of D2O on the antifungal activity, suggest the intermediacy of singlet oxygen produced by electronic excitation of the phenylphenalenone phytoalexins.

AB - The light-induced singlet oxygen production and antifungal activity of phenylphenalenone phytoalexins isolated from infected banana plants (Musa acuminata) are reported. Upon absorption of light energy all studied phenylphenalenones sensitise the production of singlet oxygen in polar and non-polar media. Antifungal activity of these compounds towards Fusarium oxysporum is enhanced in the presence of light. These results, together with the correlation of IC50 values under illumination with the quantum yield of singlet oxygen production and the enhancing effect of D2O on the antifungal activity, suggest the intermediacy of singlet oxygen produced by electronic excitation of the phenylphenalenone phytoalexins.

KW - Phenalenone-type phytoalexins

KW - Musa-acuminata

KW - Natural-products

KW - Resistance

KW - Deactivation

KW - Accumulation

KW - Generation

KW - Defense

KW - Plants

KW - Yields

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AN - SCOPUS:4344596904

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SP - 706

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JO - Photochemical and Photobiological Sciences

JF - Photochemical and Photobiological Sciences

IS - 7

ER -

Light- and singlet oxygen-mediated antifungal activity of phenylphenalenone phytoalexins

Abstract

Keywords

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