Intermediate scale for assessment of Parkinson's disease. Characteristics and structure

P. Martínez-Martin, A. Gil-Nagel, L. Morlán Gracia, J. Balseiro Gómez, F. J. Martínez-Sarriés, F. Bermejo, T. Del Ser Quijano, M. C. Macías, C. Jiménez-Rojas, E. Marañón, J. M. Grau Veciana, C. Roig Arnall, O. Bruna, C. JunquéPlaja, S. Giménez-Roldán, J. A. Burguera

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31 Citations (Scopus)


The present study is devoted to the verification of the basic metrical characteristics of the ISAPD. One hundred and sixty-seven Parkinson's disease (PD) patients were included. Group A (n = 40) was simultaneously assessed by five raters who applied the ISAPD and other PD rating scales (PDRS). A set of timed tests, the MiniMental State Examination (MMSE) and the Hamilton Scale for Depression (HSD) were administered by an independent examiner. Group B (n = 127) was individually assessed through the UPDRS and the other PDRSs by separate neurologists in four different hospitals. The ISAPD was administered in 7.0 ± 3.7 min. The internal consistency of this scale was high (Cronbach's alpha = 0.97). The inter-rater reliability of their items was very satisfactory (for all items, kappa > 0.70). There was a high correlation with the Hoehn and Yahr classification (rs = 0.71; p < 0.001) and some timed tests. The convergent validity with the other PDRS (UPDRS and Schwab and England Scale) was also very high (rs = 0.83-0.92; p < 0.001). The ISAPD also correlated with the MMSE and the HSD. Factor analysis identified three factors (activities of daily living; gait and mobility; speech and eating) that explained 76% of the variance. The ISAPD is an easy to apply, reliable, and valid scale that fulfills the aim for which it was designed.

Original languageEnglish
Pages (from-to)97-102
Number of pages6
JournalParkinsonism and Related Disorders
Issue number2
Publication statusPublished - Oct 1995
Externally publishedYes


  • Assessment
  • Intermediate Scale for Assessment of Parkinson's Disease (ISAPD)
  • Parkinson's disease
  • Scales


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