Impact of human immunodeficiency virus coinfection on the progression of mother-to-child transmitted hepatitis C virus infection

Emilia Sánchez Ruiz, Gemma Claret-Teruel, Antoni Noguera-Julián, Carmen Muñoz-Almagro, Rafael Jiménez, Clàudia Fortuny

Research output: Indexed journal article Articlepeer-review

8 Citations (Scopus)

Abstract

Data on mother-to-child transmitted human immunodeficiency virus/hepatitis C virus (HIV/HCV) coinfection are scarce. A prospective observational study with a cohort of 70 HCV-infected children (13 of whom were HIV/HCV-coinfected; mean follow-up: 7.3 years) is presented. In our series, surrogate markers of disease progression (HCV viremia, maximum alanine aminotransferase values, and spontaneous HCV infection clearance) suggest that the evolution of liver disease in HIV/HCV-coinfected pediatric patients is more aggressive than it is in HCV-only infected children.
Original languageEnglish
Pages (from-to)801-804
Number of pages4
JournalPediatric Infectious Disease Journal
Volume30
Issue number9
DOIs
Publication statusPublished - 1 Sept 2011

Keywords

  • Antiretrovil therapy
  • Hepatitis C Virus
  • Coinfection/epidemiology
  • Human Immunodeficiency virus
  • Mother-to-child transmission

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