Abstract
The efficient asymmetric protonation of lithium enolates of 2- alkylcycloalkanones (87-96% ee) with readily accessible chiral α-sulfinyl alcohols is described. Optimal stereoselection is achieved for each lithium enolate at a different reaction temperature in the range -40 to -100°C.
Original language | English |
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Pages (from-to) | 4073-4078 |
Number of pages | 6 |
Journal | Tetrahedron Asymmetry |
Volume | 9 |
Issue number | 22 |
DOIs | |
Publication status | Published - 27 Nov 1998 |
Externally published | Yes |