Cu-catalyzed tandem C-N bond formation for the synthesis of pyrroles and heteroarylpyrroles

Rubén Martín; Catharine H. Larsen; Ana Cuenca; Stephen L. Buchwald

doi:10.1021/ol7014225

Cu-catalyzed tandem C-N bond formation for the synthesis of pyrroles and heteroarylpyrroles

Rubén Martín
, Catharine H. Larsen
, Ana Cuenca
, Stephen L. Buchwald^*

^*Corresponding author for this work

Research output: Indexed journal article › Article › peer-review

149 Citations (Scopus)

Abstract

A highly efficient Cu-catalyzed tandem C-N bond-forming reaction of 1,4-dihalo-1,3-dienes has been developed. The transformation allows the synthesis of pyrroles arid heteroarylpyrroles with a wide variety of functional groups and substitution patterns from readily available precursors.

Original language	English
Pages (from-to)	3379-3382
Number of pages	4
Journal	Organic Letters
Volume	9
Issue number	17
DOIs	https://doi.org/10.1021/ol7014225
Publication status	Published - 16 Aug 2007
Externally published	Yes

Keywords

Efficient synthesis
Domino reactions
Copper
Cyclization
Chemistry
Derivatives
Ullmann
Amines
Amides

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10.1021/ol7014225

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abstract = "A highly efficient Cu-catalyzed tandem C-N bond-forming reaction of 1,4-dihalo-1,3-dienes has been developed. The transformation allows the synthesis of pyrroles arid heteroarylpyrroles with a wide variety of functional groups and substitution patterns from readily available precursors.",

keywords = "Efficient synthesis, Domino reactions, Copper, Cyclization, Chemistry, Derivatives, Ullmann, Amines, Amides",

author = "Rub{\'e}n Mart{\'i}n and Larsen, \{Catharine H.\} and Ana Cuenca and Buchwald, \{Stephen L.\}",

year = "2007",

month = aug,

day = "16",

doi = "10.1021/ol7014225",

language = "English",

volume = "9",

pages = "3379--3382",

journal = "Organic Letters",

issn = "1523-7060",

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T1 - Cu-catalyzed tandem C-N bond formation for the synthesis of pyrroles and heteroarylpyrroles

AU - Martín, Rubén

AU - Larsen, Catharine H.

AU - Cuenca, Ana

AU - Buchwald, Stephen L.

PY - 2007/8/16

Y1 - 2007/8/16

N2 - A highly efficient Cu-catalyzed tandem C-N bond-forming reaction of 1,4-dihalo-1,3-dienes has been developed. The transformation allows the synthesis of pyrroles arid heteroarylpyrroles with a wide variety of functional groups and substitution patterns from readily available precursors.

AB - A highly efficient Cu-catalyzed tandem C-N bond-forming reaction of 1,4-dihalo-1,3-dienes has been developed. The transformation allows the synthesis of pyrroles arid heteroarylpyrroles with a wide variety of functional groups and substitution patterns from readily available precursors.

KW - Efficient synthesis

KW - Domino reactions

KW - Copper

KW - Cyclization

KW - Chemistry

KW - Derivatives

KW - Ullmann

KW - Amines

KW - Amides

UR - https://www.scopus.com/pages/publications/34548181107

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:000248658800046&DestLinkType=FullRecord&DestApp=WOS_CPL

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DO - 10.1021/ol7014225

M3 - Article

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VL - 9

SP - 3379

EP - 3382

JO - Organic Letters

JF - Organic Letters

IS - 17

ER -

Cu-catalyzed tandem C-N bond formation for the synthesis of pyrroles and heteroarylpyrroles

Abstract

Keywords

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