Cu-catalyzed tandem C-N bond formation for the synthesis of pyrroles and heteroarylpyrroles

Rubén Martín, Catharine H. Larsen, Ana Cuenca, Stephen L. Buchwald

Research output: Indexed journal article Articlepeer-review

146 Citations (Scopus)

Abstract

A highly efficient Cu-catalyzed tandem C-N bond-forming reaction of 1,4-dihalo-1,3-dienes has been developed. The transformation allows the synthesis of pyrroles arid heteroarylpyrroles with a wide variety of functional groups and substitution patterns from readily available precursors.

Original languageEnglish
Pages (from-to)3379-3382
Number of pages4
JournalOrganic Letters
Volume9
Issue number17
DOIs
Publication statusPublished - 16 Aug 2007
Externally publishedYes

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