Bronchiolitis obliterans after hematopoietic stem cell transplantation

A. Roca Noval; M. Erro; M. Hernández; C. Acosta; L. Diab; R. M. Girón

Bronchiolitis obliterans after hematopoietic stem cell transplantation

A. Roca Noval, M. Erro, M. Hernández, C. Acosta, L. Diab, R. M. Girón

Research output: Indexed journal article › Article › peer-review

Abstract

Hematopoietic stem cell transplantation is an established treatment with a high curative potential for various hematological diseases. Chronic graft-versus-host disease is a major complication of this procedure and is the leading cause of late mortality after transplantation. Bronchiolitis obliterans is a particularly serious complication that occurs in 10-15% of patients with extensive graft-versus-host disease and is often refractory to treatment. If there is no response to conventional immunosuppressive treatment after 3-6 months of treatment, the prognosis of these patients is unfortunate. We report the case of a 57 year old woman diagnosed with a chronic T lymphoproliferative syndrome who developed bronchiolitis obliterans one year after an hematopoietic stem cell transplantation.

Translated title of the contribution	Bronquiolitis obliterante tras trasplante de progenitores hematopoyéticos
Original language	English
Pages (from-to)	97-100
Number of pages	4
Journal	Revista de Patologia Respiratoria
Volume	20
Issue number	3
Publication status	Published - 1 Jul 2017
Externally published	Yes

Keywords

Bronchiolitis obliterans
Chronic graft-versus-host disease
Hematopoietic stem cell transplantation

Cite this

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title = "Bronchiolitis obliterans after hematopoietic stem cell transplantation",

abstract = "Hematopoietic stem cell transplantation is an established treatment with a high curative potential for various hematological diseases. Chronic graft-versus-host disease is a major complication of this procedure and is the leading cause of late mortality after transplantation. Bronchiolitis obliterans is a particularly serious complication that occurs in 10-15% of patients with extensive graft-versus-host disease and is often refractory to treatment. If there is no response to conventional immunosuppressive treatment after 3-6 months of treatment, the prognosis of these patients is unfortunate. We report the case of a 57 year old woman diagnosed with a chronic T lymphoproliferative syndrome who developed bronchiolitis obliterans one year after an hematopoietic stem cell transplantation.",

keywords = "Bronchiolitis obliterans, Chronic graft-versus-host disease, Hematopoietic stem cell transplantation",

author = "{Roca Noval}, A. and M. Erro and M. Hern{\'a}ndez and C. Acosta and L. Diab and Gir{\'o}n, {R. M.}",

note = "Funding Information: 5. Jagasia MH, Greinix TH, Arora M, Williams KM, Wolff D, Cowen EW, et al. National Institutes of Health Consensus Development Project on Criteria For Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Stanging Working Group Report. Biol Blood Marrow Transplant. 2015; 21: 389-401.",

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month = jul,

day = "1",

language = "English",

volume = "20",

pages = "97--100",

journal = "Revista de Patologia Respiratoria",

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TY - JOUR

T1 - Bronchiolitis obliterans after hematopoietic stem cell transplantation

AU - Roca Noval, A.

AU - Erro, M.

AU - Hernández, M.

AU - Acosta, C.

AU - Diab, L.

AU - Girón, R. M.

N1 - Funding Information: 5. Jagasia MH, Greinix TH, Arora M, Williams KM, Wolff D, Cowen EW, et al. National Institutes of Health Consensus Development Project on Criteria For Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Stanging Working Group Report. Biol Blood Marrow Transplant. 2015; 21: 389-401.

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Hematopoietic stem cell transplantation is an established treatment with a high curative potential for various hematological diseases. Chronic graft-versus-host disease is a major complication of this procedure and is the leading cause of late mortality after transplantation. Bronchiolitis obliterans is a particularly serious complication that occurs in 10-15% of patients with extensive graft-versus-host disease and is often refractory to treatment. If there is no response to conventional immunosuppressive treatment after 3-6 months of treatment, the prognosis of these patients is unfortunate. We report the case of a 57 year old woman diagnosed with a chronic T lymphoproliferative syndrome who developed bronchiolitis obliterans one year after an hematopoietic stem cell transplantation.

AB - Hematopoietic stem cell transplantation is an established treatment with a high curative potential for various hematological diseases. Chronic graft-versus-host disease is a major complication of this procedure and is the leading cause of late mortality after transplantation. Bronchiolitis obliterans is a particularly serious complication that occurs in 10-15% of patients with extensive graft-versus-host disease and is often refractory to treatment. If there is no response to conventional immunosuppressive treatment after 3-6 months of treatment, the prognosis of these patients is unfortunate. We report the case of a 57 year old woman diagnosed with a chronic T lymphoproliferative syndrome who developed bronchiolitis obliterans one year after an hematopoietic stem cell transplantation.

KW - Bronchiolitis obliterans

KW - Chronic graft-versus-host disease

KW - Hematopoietic stem cell transplantation

UR - http://www.scopus.com/inward/record.url?scp=85031760352&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:85031760352

SN - 1576-9895

VL - 20

SP - 97

EP - 100

JO - Revista de Patologia Respiratoria

JF - Revista de Patologia Respiratoria

IS - 3

ER -

Bronchiolitis obliterans after hematopoietic stem cell transplantation

Abstract

Keywords

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