Aplicación de la teoría de decisión racional en la selección de un antibiótico

Translated title of the contribution: Application of the theory of rational decision in the selection of an antibiotic

Concepción Mestres Miralles, José Miralles Vera

Research output: Indexed journal article Article

Abstract

We have used the theory of the rational decision in the selection of an antibiotic in our hospital for the empirical treatment of pneumonias of a communal origin in patients aged over 65 years with risk pathologies. We identified 9 possible antibiotics. The criteria of evaluation were their activity against various germs, toxicity, dosage schedule, cost and administration routes. These criteria were evaluated by means of a survey of internists, pneumologists, emergency service doctors and pharmacists. The antibiotic that achieved the highest score was doxycycline, although it did not meet the second most highly rated criterion in the survey, which was absence of toxicity. The second-placed one was cefuroxime, which does meet it. Surprisingly, cefonicid, which was put forward by several of the agents surveyed, was placed in eighth position. On the basis of the results we conclude that this method may be useful in drug selection and we have decided to recommend the inclusion of cefuroxime in the Pharmacological Guide of the hospital.
Translated title of the contributionApplication of the theory of rational decision in the selection of an antibiotic
Original languageSpanish
Pages (from-to)10-20
Number of pages11
JournalFarmacia clínica
Volume9
Publication statusPublished - 1 Jan 1992

Keywords

  • Antibiotic agent
  • Decision making
  • Drug choice

Fingerprint

Dive into the research topics of 'Application of the theory of rational decision in the selection of an antibiotic'. Together they form a unique fingerprint.

Cite this