Anthracene-based fluorescent nanoprobes for singlet oxygen detection in biological media

Roger Bresolí-Obach, Jaume Nos, Margarita Mora, Maria Lluïsa Sagristà, Rubén Ruiz-González, Santi Nonell

Research output: Indexed journal article Articlepeer-review

26 Citations (Scopus)


We have developed a novel singlet oxygen nanoprobe based on 9,10-anthracenedipropionic acid covalently bound to mesoporous silica nanoparticles. The nanoparticle protects the probe from interactions with proteins, which detract from its ability to detect singlet oxygen. In vitro studies show that the nanoprobe is internalized by cells and is distributed throughout the cytoplasm, thus being capable of detecting intracellularly-generated singlet oxygen.

Original languageEnglish
Pages (from-to)64-72
Number of pages9
Publication statusPublished - 15 Oct 2016


  • Anthracene dipropionic acid
  • Confocal microscopy
  • Fluorescent probe
  • HeLa cells
  • Silica nanoparticles
  • Singlet oxygen


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