Alanine-supported protic ionic liquids as efficient catalysts for aldol condensation reactions

Iuliana Cota, Francesc Medina, Rafael Gonzalez-Olmos, Miguel Iglesias

Research output: Indexed journal article Articlepeer-review

13 Citations (Scopus)


A series of novel protic ionic liquids were immobilized on alanine, a cheap readily available amino acid. These short aliphatic chain ionic liquids have a low cost of preparation, a low toxicity, and need simple synthesis/purification processes. Their catalytic activity was tested for citral-acetone and benzaldehyde-acetone condensations, two reactions with an interest for pharmacological as well as flavor and fragrance industry. Good results were obtained in terms of conversion and selectivity; moreover, the catalysts can be recycled and reused for several consecutive cycles without significant loss of activity.

Original languageEnglish
Pages (from-to)18-22
Number of pages5
JournalComptes Rendus Chimie
Issue number1
Publication statusPublished - Jan 2014
Externally publishedYes


  • Aldol condensation
  • Catalysis
  • Catalyst recycling
  • Ionic liquids
  • Supported ionic liquids


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