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Addition of ethyl bromodifluoroacetate to lactones: Reactivity and stereoselectivity

  • Ana B. Cuenca
  • , François D'Hooge
  • , Vanessa Gouge
  • , Géraldine Castelot-Deliencourt
  • , Hassan Oulyadi
  • , Eric Leclerc
  • , Philippe Jubault
  • , Xavier Pannecoucke*
  • , Jean Charles Quirion
  • *Corresponding author for this work

Research output: Indexed journal article › Article › peer-review

25 Citations (Web of Science)

Abstract

Reformatsky-type additions, under various metal-mediated activation, of ethyl bromodifluoroacetate toward a series of unactivated lactones and various sugar lactones proceeded with medium to good yields and in a completely diastereoselective manner.

Original languageEnglish
Article numberG26505ST
Pages (from-to)2627-2630
Number of pages4
JournalSynlett
Issue number17
DOIs
Publication statusPublished - 17 Oct 2005
Externally publishedYes

Keywords

  • Addition reactions
  • Carbohydrates
  • Fluorine
  • Lactones
  • Stereoselectivity

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