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Activatable photosensitizers

Research output: Book chapterChapterpeer-review

2 Citations (Web of Science)

Abstract

The controlled generation of singlet oxygen is of great interest owing to its potential. The specificity of 1O2 generation is controlled by three factors: light, O2 and a photosensitizer. Yet, nowadays some applications still require even further specificity. A possible solution is to introduce a fourth factor that can establish a control mechanism by means of an external stimuli. In this chapter, the main activation mechanisms of photosensitizers will be covered: self-quenching, energy and electron transfer and 1O2 scavengers. Some external stimuli are necessary to activate this fourth factor. Examples of these are: molecular recognition, enzymes, pH, small molecules, light activation, viscosity and even a combination of them.
Translated title of the contributionChapter 8 Activatable photosensitizers
Original languageEnglish
Title of host publicationSinglet Oxygen. Applications in Biosciences and Nanosciences
EditorsSanti Nonell, Cristina Flors
PublisherRoyal Society of Chemistry
Chapter8
Pages163-181
Number of pages18
Volume1
ISBN (Electronic)978-1-78262-801-9, 978-1-78262-220-8
ISBN (Print)978-1-78262-038-9
DOIs
Publication statusPublished - Jan 2016

Publication series

NameComprehensive Series in Photochemical & Photobiological Sciences
ISSN (Print)2041-9716
ISSN (Electronic)2041-9724

Keywords

  • Photodynamic molecular beacon
  • Singlet oxygen generation
  • Rose-bengal acetate
  • Photoinduced electron-transfer
  • Fluorogenic substrate
  • Drug-delivery
  • Tumor-cells
  • Ph
  • Therapy

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