Abstract
Gem-diborylalkenes have emerged as efficient reagents for selective cross-coupling reactions, reduction approaches and Michael additions. The synthesis of 1,1-diborylalkenes involves condensation of polyborated compounds with aldehydes or ketones followed by B–O elimination, geminal diboration of 1,1-dihaloalkenes, 1-haloalkenes or terminal alkynes, dehydrogenative borylation of alkenes, borylation of alkynylboronates and hydroboration of alkynylboronates. These new sets of reactions are general for a wide range of substrates and they can be understood to have complementary mechanisms.
Original language | English |
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Pages (from-to) | 2728-2739 |
Number of pages | 12 |
Journal | European Journal of Organic Chemistry |
Volume | 2018 |
Issue number | 22 |
DOIs | |
Publication status | Published - 15 Jun 2018 |
Keywords
- Boranes
- Borylation
- Cross-coupling
- Diboration
- Reaction mechanisms
- Stereoselectivity