A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents

Oriol Planas, Thibault Gallavardin, Santi Nonell

Research output: Indexed journal article Articlepeer-review

31 Citations (Scopus)

Abstract

Reaction of porphycene isothiocyanates with primary and secondary amines leads to the formation of thiazolo[4,5-c]porphycenes, with a substantial shift in the absorption and fluorescence spectra. The conjugates show fluorescence in the near-infrared and are capable of photosensitizing the production of the cytotoxic species singlet oxygen.

Original languageEnglish
Pages (from-to)5586-5589
Number of pages4
JournalChemical Communications
Volume51
Issue number26
DOIs
Publication statusPublished - 4 Apr 2015

Fingerprint

Dive into the research topics of 'A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents'. Together they form a unique fingerprint.

Cite this