Development of a new therapy based on protein degraders for the treatment of the diabetic foot.

Project: Research GrantsResearch

Project Details


Our vision is to preclinically developed a novel, first-in-class, therapy using aptamer-based Lysosome Targeted
Chimeras (LYTACs) to heal diabetic foot ulcers (DFUs). These LYTACs targets IL-1β and collagenases MMP-
9 and MMP-2 for degradation, all of them proteins that play key role in impaired healing in diabetic wounds.
Effective start/end date1/04/2331/03/26


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