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Collaborations and top research areas from the last five years
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EXODUS-BCL: Design and synthesis of novel dual-targeted IRAK4/BTK protein degraders to enhance therapeutic efficacy in aggressive B-cell lymphoma.
Estrada Tejedor, R. (PI), Borrell, J. I. (Researcher), Teixidó Closa, J. (Researcher), Gibert Bosch, A. (Researcher), Cuartero Albesa, A. M. (Researcher) & Puig De La Bellacasa Cazorla, R. (Researcher)
Agencia Estatal de Investigación
1/09/25 → 31/08/28
Project: Research Grants › Research
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PreClinIQS080: Estudio Preclínico Inicial de IQS080, un candidato a fármaco contra el cáncer de páncreas.
Borrell, J. I. (PI), Semino, C. E. (PI), Teixidó Closa, J. (Researcher), Estrada Tejedor, R. (Researcher), Puig De La Bellacasa Cazorla, R. (Researcher), Batllori Aguilà, X. (Researcher) & Villanueva Garatachea, A. (PI)
1/12/22 → 30/11/24
Project: Research Grants › Research
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DisX4lymph: Design and synthesis of CXCR4 allosteric inhibitors and IRAK4 degraders as potential treatments of B-cell lymphoma.
Estrada Tejedor, R. (PI), Borrell, J. I. (PI), Teixidó Closa, J. (Researcher), Gibert Bosch, A. (Researcher), Puig De La Bellacasa Cazorla, R. (Researcher) & Batllori Aguilà, X. (Researcher)
Agencia Estatal de Investigación
1/09/22 → 31/08/25
Project: Research Grants › Research
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GQF: Grup de Química Farmacèutica
Estrada Tejedor, R. (PI), Artalejo Ortega, B. (Researcher), Balfagón Costa, A. (Researcher), Batllori Aguilà, X. (Researcher), Borrell, J. I. (Researcher), Cuartero Albesa, A. M. (Researcher), Gibert Bosch, A. (Researcher), Lloveras Monserrat, M. (Researcher), Manén Freixa, L. (Researcher), Mercadé Prieto, R. (Researcher), Nomen Ribé, R. (Researcher), Puig De La Bellacasa Cazorla, R. (Researcher), Semino, C. E. (Researcher), Sempere Cebrian, J. (Researcher), Serra Hosta, E. (Researcher), Teixidó Closa, J. (Researcher), Torres Urtizberea, E. (Researcher), Arias Donaire, A. (Researcher), Gorjon-de-Pablo, G. (Researcher), Martínez-Asensio, M. (Researcher), Camaló Vila, J. (Researcher), Fernández-Remacha, D. (Researcher) & Massarico Serafim, R. A. (PI)
Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR)
1/01/22 → 30/06/25
Project: Research Groups and Network Grants › Research Groups
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PROTEOblood: Red cooperativa franco-española para el análisis de proteinopatías y el desarrollo de terapias individualizados en cánceres hematológicos
Borrell, J. I. (PI), Estrada Tejedor, R. (Researcher), Puig De La Bellacasa Cazorla, R. (Researcher) & Teixidó Closa, J. (Researcher)
1/06/19 → 31/05/22
Project: Research Grants › Research
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Design and preclinical evaluation of a first-in-class covalent reversible inhibitor of IRAK4 with immunomodulatory properties and selective anti-lymphoma effect
de Pablo, G. G., Profitos-Peleja, N., Jacobs, M., Gonzalez-Herrero, A., Parra, J., Mereu, E., Cifuentes, P., Orphali, M., Teixidó Closa, J., Esteller, M., Borrell, J. I., Estrada-Tejedor, R. & Roue, G., 15 Apr 2025, In: Cancer Research. 85, 8, 2 p.Research output: Indexed journal article › Meeting Abstract › peer-review
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Discovery of novel CXCR4 targeting compounds with antitumor activity in preclinical models of diffuse large B-cell lymphoma
Fernandez-Serrano, M., Profitos-Peleja, N., Camalo-Vila, J., Martinez-Asensio, M., Teixido, J., Borrell, J. I., Gibert, A., de la Bellacasa, R. P., Estrada-Tejedor, R. & Roue, G., 15 Apr 2025, In: Cancer Research. 85, 8Research output: Indexed journal article › Meeting Abstract › peer-review
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Rational Method for Structural Simplification as Key Step in Hit Discovery: The Case of FGFR2 and IGF1R Dual Inhibitors
Torres-Urtizberea, E., Borrell, J. I., Puig de la Bellacasa, R. & Estrada-Tejedor, R., May 2025, In: International Journal of Molecular Sciences. 26, 9, 16 p., 4457.Research output: Indexed journal article › Article › peer-review
Open Access -
Applying Molecular Modeling to the Design of Innovative, Non-Symmetrical CXCR4 Inhibitors with Potent Anticancer Activity
Martínez-Asensio, M., Sàrrias, L., Gorjón-de-Pablo, G., Fernández-Serrano, M., Camaló-Vila, J., Gibert, A., Puig de la Bellacasa, R., Teixidó, J., Roué, G., Borrell, J. I. & Estrada-Tejedor, R., Sept 2024, In: International Journal of Molecular Sciences. 25, 17, 14 p., 9446.Research output: Indexed journal article › Article › peer-review
Open Access -
Autocatalytic photoinduced oxidative dehydrogenation of pyrido[2,3-d]pyrimidin-7(8H)-ones: synthesis of C5-C6 unsaturated systems with concomitant formation of a long-lived radical
de Rocafiguera, C., Lloveras, V., Vidal-Gancedo, J., Teixidó, J., Estrada-Tejedor, R., Borrell, J. I. & Puig de la Bellacasa, R., 7 Jan 2024, In: Organic Chemistry Frontiers. 11, 1, p. 27-36 11 p.Research output: Indexed journal article › Article › peer-review
Open Access2 Citations (Scopus)
Datasets
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Early Preclinical Study of IQS080, a Drug Candidate against Pancreatic Cancer
Borrell Bilbao, J. I. (Creator), Universitat Ramon Llull, 11 Feb 2025
DOI: 10.34810/data1945
Dataset
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Replication Data for: ADMET free online prediction tools for academic or small biotech environments
Estrada Tejedor, R. (Creator) & Borrell Bilbao, J. I. (Creator), Universitat Ramon Llull, 16 Jan 2023
DOI: 10.34810/data526
Dataset