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Collaborations and top research areas from the last five years
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EXODUS-BCL: Design and synthesis of novel dual-targeted IRAK4/BTK protein degraders to enhance therapeutic efficacy in aggressive B-cell lymphoma.
Estrada Tejedor, R. (PI), Borrell, J. I. (Researcher), Teixidó Closa, J. (Researcher), Gibert Bosch, A. (Researcher), Cuartero Albesa, A. M. (Researcher) & Puig De La Bellacasa Cazorla, R. (Researcher)
Agencia Estatal de Investigación
1/09/25 → 31/08/28
Project: Research Grants › Research
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PreClinIQS080: Estudio Preclínico Inicial de IQS080, un candidato a fármaco contra el cáncer de páncreas.
Borrell, J. I. (PI), Semino, C. E. (PI), Teixidó Closa, J. (Researcher), Estrada Tejedor, R. (Researcher), Puig De La Bellacasa Cazorla, R. (Researcher), Batllori Aguilà, X. (Researcher) & Villanueva Garatachea, A. (PI)
1/12/22 → 30/11/24
Project: Research Grants › Research
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DisX4lymph: Design and synthesis of CXCR4 allosteric inhibitors and IRAK4 degraders as potential treatments of B-cell lymphoma.
Estrada Tejedor, R. (PI), Borrell, J. I. (PI), Teixidó Closa, J. (Researcher), Gibert Bosch, A. (Researcher), Puig De La Bellacasa Cazorla, R. (Researcher) & Batllori Aguilà, X. (Researcher)
Agencia Estatal de Investigación
1/09/22 → 31/08/25
Project: Research Grants › Research
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GQF: Grup de Química Farmacèutica
Estrada Tejedor, R. (PI), Artalejo Ortega, B. (Researcher), Balfagón Costa, A. (Researcher), Batllori Aguilà, X. (Researcher), Borrell, J. I. (Researcher), Cuartero Albesa, A. M. (Researcher), Gibert Bosch, A. (Researcher), Lloveras Monserrat, M. (Researcher), Manén Freixa, L. (Researcher), Mercadé Prieto, R. (Researcher), Nomen Ribé, R. (Researcher), Puig De La Bellacasa Cazorla, R. (Researcher), Semino, C. E. (Researcher), Sempere Cebrian, J. (Researcher), Serra Hosta, E. (Researcher), Teixidó Closa, J. (Researcher), Torres Urtizberea, E. (Researcher), Arias Donaire, A. (Researcher), Gorjon-de-Pablo, G. (Researcher), Martínez-Asensio, M. (Researcher), Camaló Vila, J. (Researcher), Fernández-Remacha, D. (Researcher) & Massarico Serafim, R. A. (PI)
Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR)
1/01/22 → 30/06/25
Project: Research Groups and Network Grants › Research Groups
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PROTEOblood: Red cooperativa franco-española para el análisis de proteinopatías y el desarrollo de terapias individualizados en cánceres hematológicos
Borrell, J. I. (PI), Estrada Tejedor, R. (Researcher), Puig De La Bellacasa Cazorla, R. (Researcher) & Teixidó Closa, J. (Researcher)
1/06/19 → 31/05/22
Project: Research Grants › Research
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Exploring the unexplored chemical space: Rational identification of new Tafenoquine analogs with antimalarial properties
Manén Freixa, L., Moliner-Cubel, S., Gamo, F. J., Crespo, B., Borrell, J. I., Teixidó, J. & Estrada-Tejedor, R., Jul 2024, In: Bioorganic Chemistry. 148, 11 p., 107472.Research output: Indexed journal article › Article › peer-review
1 Citation (Scopus) -
Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma
Recasens-Zorzo, C., Cardesa-Salzmann, T., Petazzi, P., Ros-Blanco, L., Esteve-Arenys, A., Clot, G., Guerrero-Hernández, M., Rodríguez, V., Soldini, D., Valera, A., Moros, A., Climent, F., González-Barca, E., Mercadal, S., Arenillas, L., Calvo, X., Mate, J. L., Gutiérrez-García, G., Casanova, I. & Mangues, R. & 13 others, , 31 Mar 2019, In: Haematologica. 104, 4, p. 778-788 11 p.Research output: Indexed journal article › Article › peer-review
Open Access24 Citations (Web of Science) -
In silico discovery of substituted pyrido[2,3-d] pyrimidines and pentamidine-like compounds with biological activity in myotonic dystrophy models
Gonzalez, À. L., Konieczny, P., Llamusi, B., Delgado-Pinar, E., Borrell, J. I., Teixidó, J., García-España, E., Pérez-Alonso, M., Estrada-Tejedor, R. & Artero, R., Jun 2017, In: PLoS ONE. 12, 6, 23 p., 0178931.Research output: Indexed journal article › Article › peer-review
Open Access17 Citations (Scopus) -
Nitrogen positional scanning in tetramines active against HIV-1 as potential CXCR4 inhibitors
Puig De La Bellacasa, R., Gibert, A., Planesas, J. M., Ros-Blanco, L., Batllori, X., Badía, R., Clotet, B., Esté, J., Teixidó, J. & Borrell, J. I., 2016, In: Organic and Biomolecular Chemistry. 14, 4, p. 1455-1472 18 p.Research output: Indexed journal article › Article › peer-review
Open Access3 Citations (Scopus) -
Highly specific and sensitive pharmacophore model for identifying CXCR4 antagonists. Comparison with docking and shape-matching virtual screening performance
Karaboga, A. S., Planesas, J. M., Petronin, F., Teixidó, J., Souchet, M. & Pérez-Nueno, V. I., 24 May 2013, In: Journal of Chemical Information and Modeling. 53, 5, p. 1043-1056 14 p.Research output: Indexed journal article › Article › peer-review
19 Citations (Scopus)