Research output per year
Research output per year
- 28 results
Search results
-
2024
Loss of Cldn5 -and increase in Irf7-in the hippocampus and cerebral cortex of diabetic mice at the early symptomatic stage
Carús-Cadavieco, M., González de la Fuente, S., Berenguer López, I., Serrano-Lope, M. A., Aguado, B., Guix, F., Palomer, E. & Dotti, C. G., 15 Aug 2024, In: Nutrition and Diabetes. 14, 1, 6 p., 64.Research output: Indexed journal article › Article › peer-review
Open Access -
2023
Cognitive decline in diabetic mice predisposed to Alzheimer’s disease is greater than in wild type
Carús-Cadavieco, M., López, I. B., Montoro Canelo, A., Serrano-Lope, M. A., González de la Fuente, S., Aguado, B., Fernández-Rodrigo, A., Saido, T. C., García, A. F., Venero, C., Esteban, J. A., Guix, F. & Dotti, C. G., Jun 2023, In: Life Science Alliance. 6, 6, 20 p., e202201789.Research output: Indexed journal article › Article › peer-review
Open Access6 Citations (Scopus) -
Neuronal prosurvival role of ceramide synthase 2 by olidogendrocyte-to-neuron extracellular vesicle transfer
Casadomé-Perales, Á., Naya, S., Fernández-Martínez, E., Mille, B. G., Guerrero-Valero, M., Peinado, H., Guix, F. X., Dotti, C. G. & Palomer, E., Mar 2023, In: International Journal of Molecular Sciences. 24, 6, 17 p., 5986.Research output: Indexed journal article › Article › peer-review
Open Access2 Citations (Scopus) -
2022
Extracellular Vesicles Derived from Young Neural Cultures Attenuate Astrocytic Reactivity In Vitro
Almansa, D., Peinado, H., García‐rodríguez, R., Casadomé‐perales, Á., Dotti, C. G. & Guix, F. X., 1 Feb 2022, In: International Journal of Molecular Sciences. 23, 3, 16 p., 1371.Research output: Indexed journal article › Article › peer-review
Open Access4 Citations (Scopus) -
2021
Enhancing Anti-Aβ Properties of Recombinant Autoantibodies
Guix, F. X., 21 May 2021, In: Neuroscience. 463, p. 354 1 p.Research output: Indexed journal article › Editorial
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Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup
Guix, F. X., Capitán, A. M., Casadomé-Perales, Á., Palomares-Pérez, I., del Castillo, I. L., Miguel, V., Goedeke, L., Martín, M. G., Lamas, S., Peinado, H., Fernández-Hernando, C. & Dotti, C. G., Jun 2021, In: Life Science Alliance. 4, 8, 18 p., e202101055.Research output: Indexed journal article › Article › peer-review
Open Access21 Citations (Scopus) -
2020
Amyloid beta-peptide increases BACE1 translation through the phosphorylation of the eukaryotic initiation factor-2 alpha
Picon-Pages, P., Gutierrez, D. A., Barranco-Almohalla, A., Crepin, G., Tajes, M., Ill-Raga, G., Guix, F. X., Menendez, S., Arumí-Uría, M., Vicente, R., Alvarez, A. R. & Munoz, F. J., 21 Sept 2020, In: Oxidative Medicine and Cellular Longevity. 2020, 12 p., 2739459.Research output: Indexed journal article › Article › peer-review
Open Access13 Citations (Web of Science) -
Amyloid Beta-Peptide Increases BACE1 Translation through the Phosphorylation of the Eukaryotic Initiation Factor-2 α
Picón-Pagès, P., Gutiérrez, D. A., Barranco-Almohalla, A., Crepin, G., Tajes, M., Ill-Raga, G., Guix, F. X., Menéndez, S., Arumí-Uría, M., Vicente, R., Álvarez, A. R. & Muñoz, F. J., 2020, In: Oxidative Medicine and Cellular Longevity. 2020, 2739459.Research output: Indexed journal article › Article › peer-review
Open Access14 Citations (Scopus) -
Prodromal Alzheimer’s Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer’s Pathology
de Vidania, S., Palomares-Perez, I., Frank-García, A., Saito, T., Saido, T. C., Draffin, J., Szaruga, M., Chávez-Gutierrez, L., Calero, M., Medina, M., Guix, F. X. & Dotti, C. G., 3 Dec 2020, In: Frontiers in Neuroscience. 14, 562581.Research output: Indexed journal article › Article › peer-review
Open Access12 Citations (Scopus) -
The interplay between aging-associated loss of protein homeostasis and extracellular vesicles in neurodegeneration
Guix, F. X., 1 Feb 2020, In: Journal of Neuroscience Research. 98, 2, p. 262-283 22 p.Research output: Indexed journal article › Review › peer-review
23 Citations (Scopus) -
2019
BACE1 translation: At the crossroads between Alzheimer's disease neurodegeneration and memory consolidation
Guix, F. X., Sartório, C. L. & Ill-Raga, G., May 2019, In: Journal of Alzheimer's Disease Reports. 3, 1, p. 113-148 36 p.Research output: Indexed journal article › Review › peer-review
Open Access9 Citations (Scopus) -
2018
Could blocking the formation of amyloid channels rescue Alzheimer's phenotype?
Guix, F. X. & Dotti, C. G., Jan 2018, In: EMBO Molecular Medicine. 10, 1, p. 7-9 3 p.Research output: Indexed journal article › Comment/debate
Open Access3 Citations (Scopus) -
Detection of aggregation-competent tau in neuron-derived extracellular vesicles
Guix, F. X., Corbett, G. T., Cha, D. J., Mustapic, M., Liu, W., Mengel, D., Chen, Z., Aikawa, E., Young-Pearse, T., Kapogiannis, D., Selkoe, D. J. & Walsh, D. M., Mar 2018, In: International Journal of Molecular Sciences. 19, 3, 663.Research output: Indexed journal article › Article › peer-review
Open Access145 Citations (Scopus) -
2017
Correction: Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity (PLoS ONE) (2017) 12:2 (e0171968) DOI: 10.1371/journal.pone.0171968)
Salas, I. H., Callaerts-Vegh, Z., Arranz, A. M., Guix, F. X., D’Hooge, R., Esteban, J. A., De Strooper, B. & Dotti, C. G., Jul 2017, In: PLoS ONE. 12, 7, e0178016.Research output: Indexed journal article › Comment/debate
Open Access1 Citation (Scopus) -
Tetraspanin 6: A pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments
Guix, F. X., Sannerud, R., Berditchevski, F., Arranz, A. M., Horré, K., Snellinx, A., Thathiah, A., Saido, T., Saito, T., Rajesh, S., Overduin, M., Kumar-Singh, S., Radaelli, E., Corthout, N., Colombelli, J., Tosi, S., Munck, S., Salas, I. H., Annaert, W. & De Strooper, B., 10 Mar 2017, In: Molecular Neurodegeneration. 12, 1, 21 p., 25.Research output: Indexed journal article › Article › peer-review
Open Access79 Citations (Scopus) -
Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity
Salas, I. H., Callaerts-Vegh, Z., Arranz, A. M., Guix, F. X., D'Hooge, R., Esteban, J. A., De Strooper, B. & Dotti, C. G., 16 Feb 2017, In: PLoS ONE. 12, 2, 21 p., e0171968.Research output: Indexed journal article › Article › peer-review
Open Access15 Citations (Web of Science) -
2015
Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death
ILL-Raga, G., Palomer, E., Ramos-Fernández, E., Guix, F. X., Bosch-Morató, M., Guivernau, B., Tajes, M., Valls-Comamala, V., Jiménez-Conde, J., Ois, A., Pérez-Asensio, F., Reyes-Navarro, M., Caballo, C., Gil-Gómez, G., Lopez-Vilchez, I., Galan, A. M., Alameda, F., Escolar, G., Opazo, C. & Planas, A. M. & 3 others, , 1 Mar 2015, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 3, p. 421-428 8 p.Research output: Indexed journal article › Article › peer-review
Open Access24 Citations (Scopus) -
Physiological Control of Nitric Oxide in Neuronal BACE1 Translation by Heme-Regulated eIF2 alpha Kinase HRI Induces Synaptogenesis
ILL-Raga, G., Tajes, M., Busquets-Garcia, A., Ramos-Fernandez, E., Vargas, L. M., Bosch-Morato, M., Guivernau, B., Valls-Comamala, V., Eraso-Pichot, A., Guix, F. X., Fandos, C., Rosen, M. D., Rabinowitz, M. H., Maldonado, R., Alvarez, A. R., Ozaita, A. & Munoz, F. J., 20 May 2015, In: Antioxidants and Redox Signaling. 22, 15, p. 1295-1307 13 p.Research output: Indexed journal article › Article › peer-review
28 Citations (Scopus) -
2014
Methylglyoxal produced by amyloid-beta peptide-induced nitrotyrosination of triosephosphate isomerase triggers neuronal death in alzheimer's disease
Tajes, M., Eraso-Pichot, A., Rubio-Moscardo, F., Guivernau, B., Ramos-Fernandez, E., Bosch-Morato, M., Xavier Guix, F., Clarimon, J., Pietro Miscione, G., Boada, M., Gil-Gomez, G., Suzuki, T., Molina, H., Villa-Freixa, J., Vicente, R. & Munoz, F. J., 2014, In: Journal of Alzheimer's Disease. 41, 1, p. 273-288 16 p.Research output: Indexed journal article › Article › peer-review
39 Citations (Scopus) -
2013
Nitro-oxidative stress after neuronal ischemia induces protein nitrotyrosination and cell death
Tajes, M., Ill-Raga, G., Palomer, E., Ramos-Fernández, E., Guix, F. X., Bosch-Morató, M., Guivernau, B., Jiménez-Conde, J., Ois, A., Pérez-Asensio, F., Reyes-Navarro, M., Caballo, C., Galán, A. M., Alameda, F., Escolar, G., Opazo, C., Planas, A., Roquer, J., Valverde, M. A. & Muñoz, F. J., 2013, In: Oxidative Medicine and Cellular Longevity. 9 p., 826143.Research output: Indexed journal article › Article › peer-review
Open Access44 Citations (Scopus) -
The pathophysiology of triose phosphate isomerase dysfunction in alzheimer's disease
Tajes, M., Guivernau, B., Ramos-Fernández, E., Bosch-Morató, M., Palomer, E., Guix, F. X. & Muñoz, F. J., Jan 2013, In: Histology and Histopathology. 28, 1, p. 43-51 9 p.Research output: Indexed journal article › Review › peer-review
24 Citations (Scopus) -
2012
Alterations in phosphatidylethanolamine levels affect the generation of Aβ
Nesic, I., Guix, F. X., Vennekens, K., Michaki, V., Van Veldhoven, P. P., Feiguin, F., De Strooper, B., Dotti, C. G. & Wahle, T., Feb 2012, In: Aging Cell. 11, 1, p. 63-72 10 p.Research output: Indexed journal article › Article › peer-review
Open Access30 Citations (Scopus) -
Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering nicastrin maturation and intracellular localization
Michaki, V., Guix, F. X., Vennekens, K., Munck, S., Dingwall, C., Davis, J. B., Townsend, D. M., Tew, K. D., Feiguin, F., De Strooper, B., Dotti, C. G. & Wahle, T., 6 Jan 2012, In: Journal of Biological Chemistry. 287, 2, p. 1100-1111 12 p.Research output: Indexed journal article › Article › peer-review
Open Access36 Citations (Scopus) -
Modification of gamma-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease
Guix, F. X., Wahle, T., Vennekens, K., Snellinx, A., Chavez-Gutierrez, L., Ill-Raga, G., Ramos-Fernandez, E., Guardia-Laguarta, C., Lleo, A., Arimon, M., Berezovska, O., Munoz, F. J., Dotti, C. G. & De Strooper, B., Jul 2012, In: EMBO Molecular Medicine. 4, 7, p. 660-673 14 p.Research output: Indexed journal article › Article › peer-review
Open Access71 Citations (Scopus) -
2011
Activation of PKR causes amyloid ß-peptide accumulation via De-Repression of Bace1 expression
ILL-Raga, G., Palomer, E., Wozniak, M. A., Ramos-Fernández, E., Bosch-Morató, M., Tajes, M., Guix, F. X., Galán, J. J., Clarimón, J., Antúnez, C., Real, L. M., Boada, M., Itzhaki, R. F., Fandos, C. & Muñoz, F. J., 28 Jun 2011, In: PLoS ONE. 6, 6, 10 p., e21456.Research output: Indexed journal article › Article › peer-review
Open Access59 Citations (Scopus) -
2010
Amyloid-beta peptide fibrils induce nitro-oxidative stress in neuronal cells
Ill-Raga, G., Ramos-Fernández, E., Guix, F. X., Tajes, M., Bosch-Morató, M., Palomer, E., Godoy, J., Belmar, S., Cerpa, W., Simpkins, J. W., Inestrosa, N. C. & Muñoz, F. J., 2010, In: Journal of Alzheimer's Disease. 22, 2, p. 641-652 12 p.Research output: Indexed journal article › Article › peer-review
56 Citations (Scopus) -
2005
The amyloid β-protein precursor and Alzheimer's disease. Therapeutic approaches
Del Toro, D., Coma, M., Uribesalgo, I., Guix, F. X. & Muñoz, F. J., Dec 2005, In: Current Medicinal Chemistry - Central Nervous System Agents. 5, 4, p. 271-283 13 p.Research output: Indexed journal article › Review › peer-review
13 Citations (Scopus) -
The physiology and pathophysiology of nitric oxide in the brain
Guix, F., Uribesalgo, I., Coma, M. & Munoz, F., Jun 2005, In: Progress in Neurobiology. 76, 2, p. 126-152 27 p.Research output: Indexed journal article › Review › peer-review
643 Citations (Scopus)