The reaction of malononitrile with chalcone: a controversial chemical process

Pedro Victory; José I. Borrell; Anton Vidal-Ferran; Carlos Seoane; José L. Soto

doi:10.1016/S0040-4039(00)92390-6

The reaction of malononitrile with chalcone: a controversial chemical process

Pedro Victory^*
, José I. Borrell
, Anton Vidal-Ferran
, Carlos Seoane
, José L. Soto

^*Autor corresponent d’aquest treball

Producció científica: Article en revista indexada › Article › Avaluat per experts

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Given the significant discrepancies in the several reported results on the reaction of chalcone (1,3-diphenyl-2-propne-1-one) (1) with malononitrile (2), a careful reinvestigation was carried out. Depending upon the reaction conditions either the open-chain Michael adduct (4), an alkoxypyridine (5), an aminoisophthalonitrile (6) or a cyclohexanol (7) is obtained. However, no 4H-pyran could be isolated from this reaction.

Idioma original	Anglès
Pàgines (de-a)	5375-5378
Nombre de pàgines	4
Revista	Tetrahedron Letters
Volum	32
Número	39
DOIs	https://doi.org/10.1016/S0040-4039(00)92390-6
Estat de la publicació	Publicada - 23 de set. 1991

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10.1016/S0040-4039(00)92390-6

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@article{9d90d883b61d4ea78ad0a4a318bdfc23,

title = "The reaction of malononitrile with chalcone: a controversial chemical process",

abstract = "Given the significant discrepancies in the several reported results on the reaction of chalcone (1,3-diphenyl-2-propne-1-one) (1) with malononitrile (2), a careful reinvestigation was carried out. Depending upon the reaction conditions either the open-chain Michael adduct (4), an alkoxypyridine (5), an aminoisophthalonitrile (6) or a cyclohexanol (7) is obtained. However, no 4H-pyran could be isolated from this reaction.",

keywords = "2-aminoisophthalonitrile, 3-cyanopyridine, 4H-pyran, Versatile Michael addition, hexasubstituted cyclohexanol",

author = "Pedro Victory and Borrell, \{Jos{\'e} I.\} and Anton Vidal-Ferran and Carlos Seoane and Soto, \{Jos{\'e} L.\}",

year = "1991",

month = sep,

day = "23",

doi = "10.1016/S0040-4039(00)92390-6",

language = "English",

volume = "32",

pages = "5375--5378",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd.",

number = "39",

}

TY - JOUR

T1 - The reaction of malononitrile with chalcone

T2 - a controversial chemical process

AU - Victory, Pedro

AU - Borrell, José I.

AU - Vidal-Ferran, Anton

AU - Seoane, Carlos

AU - Soto, José L.

PY - 1991/9/23

Y1 - 1991/9/23

N2 - Given the significant discrepancies in the several reported results on the reaction of chalcone (1,3-diphenyl-2-propne-1-one) (1) with malononitrile (2), a careful reinvestigation was carried out. Depending upon the reaction conditions either the open-chain Michael adduct (4), an alkoxypyridine (5), an aminoisophthalonitrile (6) or a cyclohexanol (7) is obtained. However, no 4H-pyran could be isolated from this reaction.

AB - Given the significant discrepancies in the several reported results on the reaction of chalcone (1,3-diphenyl-2-propne-1-one) (1) with malononitrile (2), a careful reinvestigation was carried out. Depending upon the reaction conditions either the open-chain Michael adduct (4), an alkoxypyridine (5), an aminoisophthalonitrile (6) or a cyclohexanol (7) is obtained. However, no 4H-pyran could be isolated from this reaction.

KW - 2-aminoisophthalonitrile

KW - 3-cyanopyridine

KW - 4H-pyran

KW - Versatile Michael addition

KW - hexasubstituted cyclohexanol

UR - https://www.scopus.com/pages/publications/0025880703

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:A1991GJ03600043&DestLinkType=FullRecord&DestApp=WOS_CPL

U2 - 10.1016/S0040-4039(00)92390-6

DO - 10.1016/S0040-4039(00)92390-6

M3 - Article

AN - SCOPUS:0025880703

SN - 0040-4039

VL - 32

SP - 5375

EP - 5378

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 39

ER -

The reaction of malononitrile with chalcone: a controversial chemical process

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