The reaction of malononitrile with chalcone: a controversial chemical process

Pedro Victory; José I. Borrell; Anton Vidal-Ferran; Carlos Seoane; José L. Soto

doi:10.1016/S0040-4039(00)92390-6

The reaction of malononitrile with chalcone: a controversial chemical process

Pedro Victory, José I. Borrell, Anton Vidal-Ferran, Carlos Seoane, José L. Soto

Producció científica: Article en revista indexada › Article › Avaluat per experts

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Given the significant discrepancies in the several reported results on the reaction of chalcone (1,3-diphenyl-2-propne-1-one) (1) with malononitrile (2), a careful reinvestigation was carried out. Depending upon the reaction conditions either the open-chain Michael adduct (4), an alkoxypyridine (5), an aminoisophthalonitrile (6) or a cyclohexanol (7) is obtained. However, no 4H-pyran could be isolated from this reaction.

Idioma original	Anglès
Pàgines (de-a)	5375-5378
Nombre de pàgines	4
Revista	Tetrahedron Letters
Volum	32
Número	39
DOIs	https://doi.org/10.1016/S0040-4039(00)92390-6
Estat de la publicació	Publicada - 23 de set. 1991
Publicat externament	Sí

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title = "The reaction of malononitrile with chalcone: a controversial chemical process",

abstract = "Given the significant discrepancies in the several reported results on the reaction of chalcone (1,3-diphenyl-2-propne-1-one) (1) with malononitrile (2), a careful reinvestigation was carried out. Depending upon the reaction conditions either the open-chain Michael adduct (4), an alkoxypyridine (5), an aminoisophthalonitrile (6) or a cyclohexanol (7) is obtained. However, no 4H-pyran could be isolated from this reaction.",

keywords = "2-aminoisophthalonitrile, 3-cyanopyridine, 4H-pyran, Versatile Michael addition, hexasubstituted cyclohexanol",

author = "Pedro Victory and Borrell, {Jos{\'e} I.} and Anton Vidal-Ferran and Carlos Seoane and Soto, {Jos{\'e} L.}",

year = "1991",

month = sep,

day = "23",

doi = "10.1016/S0040-4039(00)92390-6",

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volume = "32",

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journal = "Tetrahedron Letters",

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T1 - The reaction of malononitrile with chalcone

T2 - a controversial chemical process

AU - Victory, Pedro

AU - Borrell, José I.

AU - Vidal-Ferran, Anton

AU - Seoane, Carlos

AU - Soto, José L.

PY - 1991/9/23

Y1 - 1991/9/23

N2 - Given the significant discrepancies in the several reported results on the reaction of chalcone (1,3-diphenyl-2-propne-1-one) (1) with malononitrile (2), a careful reinvestigation was carried out. Depending upon the reaction conditions either the open-chain Michael adduct (4), an alkoxypyridine (5), an aminoisophthalonitrile (6) or a cyclohexanol (7) is obtained. However, no 4H-pyran could be isolated from this reaction.

AB - Given the significant discrepancies in the several reported results on the reaction of chalcone (1,3-diphenyl-2-propne-1-one) (1) with malononitrile (2), a careful reinvestigation was carried out. Depending upon the reaction conditions either the open-chain Michael adduct (4), an alkoxypyridine (5), an aminoisophthalonitrile (6) or a cyclohexanol (7) is obtained. However, no 4H-pyran could be isolated from this reaction.

KW - 2-aminoisophthalonitrile

KW - 3-cyanopyridine

KW - 4H-pyran

KW - Versatile Michael addition

KW - hexasubstituted cyclohexanol

UR - http://www.scopus.com/inward/record.url?scp=0025880703&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)92390-6

DO - 10.1016/S0040-4039(00)92390-6

M3 - Article

AN - SCOPUS:0025880703

SN - 0040-4039

VL - 32

SP - 5375

EP - 5378

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 39

ER -

The reaction of malononitrile with chalcone: a controversial chemical process

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