Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

Pedro Victory; JoséI I. Borrell; Anton Vidal-Ferran; Elvira Montenegro; M. Luisa Jimeno

doi:10.3987/com-93-6412

Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

Pedro Victory, JoséI I. Borrell, Anton Vidal-Ferran, Elvira Montenegro, M. Luisa Jimeno

Producció científica: Article en revista indexada › Article › Avaluat per experts

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The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.

Idioma original	Anglès
Pàgines (de-a)	2273-2280
Nombre de pàgines	8
Revista	Heterocycles
Volum	36
Número	10
DOIs	https://doi.org/10.3987/com-93-6412
Estat de la publicació	Publicada - 1 d’oct. 1993

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title = "Synthesis of 4-amino-8-cyanoquinazolines from enones and enals",

abstract = "The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.",

author = "Pedro Victory and Borrell, {Jos{\'e}I I.} and Anton Vidal-Ferran and Elvira Montenegro and Jimeno, {M. Luisa}",

year = "1993",

month = oct,

day = "1",

doi = "10.3987/com-93-6412",

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T1 - Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

AU - Victory, Pedro

AU - Borrell, JoséI I.

AU - Vidal-Ferran, Anton

AU - Montenegro, Elvira

AU - Jimeno, M. Luisa

PY - 1993/10/1

Y1 - 1993/10/1

N2 - The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.

AB - The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.

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Synthesis of 4-amino-8-cyanoquinazolines from enones and enals

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