Synergistic effects of hyperosmotic polymannitol based non-viral vectors and nanotopographical cues for enhanced gene delivery

Pan Kaj Garg, Shambhavi Pandey, Hong Nam Kim, Hoon Seonwoo, Sunho Park, Kyoung Soon Choi, Kyoung Je Jang, Hoon Hyun, Phil Hoon Choung, Jangho Kim, Jong Hoon Chung

Producció científica: Article en revista indexadaArticleAvaluat per experts

3 Cites (Scopus)

Resum

Here, we report the synergistic effects of hyperosmotic and nanotopographical cues designed using non-viral vectors and nanopatterned matrices for gene delivery. We show that efficiency of gene delivery can be further enhanced by two factors in combination, indicating the importance of synergistic cues in designing non-viral gene delivery platforms and strategies for gene therapy.

Idioma originalAnglès
Pàgines (de-a)111233-111238
Nombre de pàgines6
RevistaRSC Advances
Volum6
Número112
DOIs
Estat de la publicacióPublicada - 2016
Publicat externament

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