Revisiting the ‘One Material Fits All’ Rule for Cancer Nanotherapy

João Conde, Nuria Oliva, Natalie Artzi

Producció científica: Article en revista indexadaArticle de revisió (sistemàtica)Avaluat per experts

6 Cites (Scopus)


The promise of (nano)biomaterials for the treatment of cancer can only be realized following a comprehensive scrutiny of the tumor microenvironment. The generic use of ‘inert’ vehicles that deliver a specific cargo to treat a range of cancer types and disease states obeys the ‘one material fits all’ rule. However, this approach leads to suboptimal and unpredictable clinical outcomes. The key factors constructing the tumor milieu should guide the design of disease-responsive materials. Given the growing availability of nanomaterials for cancer therapy, a material that responds to each patient's needs and, hence, reacts in a graded manner based on disease cues, would pave the way to precision materials for cancer therapy.

Idioma originalAnglès
Pàgines (de-a)618-626
Nombre de pàgines9
RevistaTrends in Biotechnology
Estat de la publicacióPublicada - 1 d’ag. 2016
Publicat externament


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