TY - JOUR
T1 - Preterm birth and early life environmental factors
T2 - neuropsychological profiles at adolescence and young adulthood
AU - Fernández de Gamarra-Oca, Lexuri
AU - Zubiaurre-Elorza, Leire
AU - Gómez-Gastiasoro, Ainara
AU - Molins-Sauri, Marta
AU - Loureiro, Begoña
AU - Peña, Javier
AU - García-Guerrero, M. Acebo
AU - Ibarretxe-Bilbao, Naroa
AU - Bruna, Olga
AU - Junqué, Carme
AU - Macaya, Alfons
AU - Poca, Maria A.
AU - Ojeda, Natalia
N1 - Funding Information:
This research was supported by the Spanish Ministry of Science, Innovation and Universities [L. Zubiaurre-Elorza (PSI2017-83657-P)]; Aristos Campus Mundus [L. Zubiaurre-Elorza (ACM2018_17)]; the Department of Education and Science of the Basque Government [N. Ojeda (IT1545-22)]; and the Department of Education of the Basque Government [L. Fernández de Gamarra-Oca (PRE_2019_1_0105)]. We would like to give special thanks to the adolescents and young adults who participated in this study.
Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer Nature America, Inc.
PY - 2023/11
Y1 - 2023/11
N2 - Objectives: To establish neuropsychological profiles after high- and low-risk preterm birth (i.e., with and without neonatal brain injury) during adolescence and young adulthood and to assess the potential role of early life environmental factors in cognition. Study design: Participants (N = 177; Mage = 20.11 years) of both sexes were evaluated when adolescent or in young adulthood. They were grouped according to their birth status: 30 high-risk preterm, 83 low-risk preterm and 64 born at full term. Results: Significant differences were found in several cognitive domains between groups. Furthermore, familial socioeconomic status (SES) moderated the relation between the degree of maturity/immaturity at birth and cognition (F (5,171) = 11.94, p < 0.001, R 2 = 0.26). Discussion: The findings showed different neuropsychological profiles during adolescence and young adulthood, with the high-risk preterm sample evidencing lower cognitive values. In addition, higher scores in the familial SES score in this study seem to have a protective effect on cognition.
AB - Objectives: To establish neuropsychological profiles after high- and low-risk preterm birth (i.e., with and without neonatal brain injury) during adolescence and young adulthood and to assess the potential role of early life environmental factors in cognition. Study design: Participants (N = 177; Mage = 20.11 years) of both sexes were evaluated when adolescent or in young adulthood. They were grouped according to their birth status: 30 high-risk preterm, 83 low-risk preterm and 64 born at full term. Results: Significant differences were found in several cognitive domains between groups. Furthermore, familial socioeconomic status (SES) moderated the relation between the degree of maturity/immaturity at birth and cognition (F (5,171) = 11.94, p < 0.001, R 2 = 0.26). Discussion: The findings showed different neuropsychological profiles during adolescence and young adulthood, with the high-risk preterm sample evidencing lower cognitive values. In addition, higher scores in the familial SES score in this study seem to have a protective effect on cognition.
KW - Born preterm
KW - Periventricular leukomalacia
KW - Socioeconomic-status
KW - Cognitive outcomes
KW - Children
KW - Infants
KW - Moderate
KW - Health
KW - Delay
UR - https://www.scopus.com/pages/publications/85164948586
UR - https://www.webofscience.com/wos/woscc/full-record/WOS:001029097300002
U2 - 10.1038/s41372-023-01727-z
DO - 10.1038/s41372-023-01727-z
M3 - Article
C2 - 37454175
AN - SCOPUS:85164948586
SN - 0743-8346
VL - 43
SP - 1429
EP - 1436
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 11
ER -